| Literature DB >> 13992691 |
Abstract
The injection of two synthetic polypeptide antigens into adult rabbits treated with 6-mercaptopurine, or into newborn rabbits, resulted in immunological "unresponsiveness" to subsequent immunizations with these antigens. The "tolerant" animals were shown to be reactive toward the non-related antigen ovalbumin.Entities:
Keywords: ANTIGENS; PEPTIDES
Mesh:
Substances:
Year: 1963 PMID: 13992691 DOI: 10.1126/science.139.3552.342
Source DB: PubMed Journal: Science ISSN: 0036-8075 Impact factor: 47.728