| Literature DB >> 13989971 |
S SPECTOR, A SJOERDSMA, P ZALTZMAN-NIRENBERG, M LEVITT, S UDENFRIEND.
Abstract
The isolated, perfused guinea pig heart contains all the catalysts required to form norepinephrine from the dietary precursor, tyrosine. The conversion of tyrosine-C(14) to norepinephrine in the perfused heart occurred at a rate comparable to that estimated for this conversion in vivo. To account for the maintenance of norepinephrine stores in the normal heart, it is not necessary to postulate that the hormone is extracted from the blood.Entities:
Keywords: MYOCARDIUM; NOREPINEPHRINE; TYROSINE
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Year: 1963 PMID： 13989971 DOI： 10.1126/science.139.3561.1299
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728