| Literature DB >> 1398950 |
M G Stevens1, G W Pugh, L B Tabatabai.
Abstract
Increased resistance to infection with Brucella abortus 2308 resulted when recombinant murine gamma interferon (rMuIFN-gamma) was given to mice both before and during infection but not when given only before infection. Mice given rMuIFN-gamma had enhanced peritoneal and splenic macrophage bactericidal activity against B. abortus. Treatment of mice with rMuIFN-gamma plus indomethacin did not further enhance resistance to infection or macrophage bactericidal activity compared with that after treatment of mice with rMuIFN-gamma alone.Entities:
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Year: 1992 PMID: 1398950 PMCID: PMC257479 DOI: 10.1128/iai.60.10.4407-4409.1992
Source DB: PubMed Journal: Infect Immun ISSN: 0019-9567 Impact factor: 3.441