Literature DB >> 13986973

Minimal dosage of iodide required to suppress uptake of iodine-131 by normal thyroid.

K M SAXENA, E M CHAPMAN, C V PRYLES.   

Abstract

Sodium iodide was given in increasing doses to mentally defective children with normal thyroid function. Maximal suppression of iodine-131 uptake was achieved with 1500 to 2000 micrograms of iodide per square meter of body surface per day, but quickly rebounded when iodide was discontinued. This minimal effective dose is important if countermeasures against fallout are employed.

Entities:  

Keywords:  IODIDES; IODINE ISOTOPES; THYROID GLAND

Mesh：

Substances：

Year:  1962        PMID： 13986973     DOI： 10.1126/science.138.3538.430

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  7 in total

1.  IMPLICATIONS OF IODINE 131 IN FALLOUT.

Authors:  M F BRINK; M S READ
Journal:  Public Health Rep       Date:  1964-01       Impact factor: 2.792

2.  [DIGLYCOLIC ACID BIS(3-CARBOXY-2,4,6-TRIIODOANILIDE) (IOGLYCAMID), A NEW CONTRAST MEDIUM FOR INTRAVENOUS CHOLANGIOGRAPHY].

Authors:  H LANGECKER; A HARWART; K H KOLB; M KRAMER
Journal:  Naunyn Schmiedebergs Arch Exp Pathol Pharmakol       Date:  1964-07-28

3.  Clinical dilemmas arising from the increased intake of iodine in the Spanish population and the recommendation for systematic prescription of potassium iodide in pregnant and lactating women (Consensus of the TDY Working Group of SEEN).

Authors:  F Soriguer; P Santiago; L Vila; J M Arena; E Delgado; F Díaz Cadórniga; S Donnay; M Fernández Soto; S González-Romero; P Martul; M Puig Domingo; S Ares; F Escobar del Rey; G Morreale de Escobar
Journal:  J Endocrinol Invest       Date:  2009-02       Impact factor: 4.256

4.  Bread iodine content and thyroid radioiodine uptake: a tale of two cities.

Authors:  B A Sachs; E Siegel; B N Horwitt; E Siegel
Journal:  Br Med J       Date:  1972-01-08

5.  Repeated KI Prophylaxis in Case of Prolonged Exposure to Iodine Radioisotopes: Pharmacokinetic Studies in Adult Rats.

Authors:  Guillaume Phan; Rym Chioukh; David Suhard; Alexandre Legrand; Charlotte Moulin; Thibaud Sontag; François Rebière; Céline Bouvier-Capely; Michelle Agarande; Valérie Renaud-Salis; Jean-René Jourdain
Journal:  Pharm Res       Date:  2018-10-08       Impact factor: 4.200

Review 6.  Use of iodine for water disinfection: iodine toxicity and maximum recommended dose.

Authors:  H Backer; J Hollowell
Journal:  Environ Health Perspect       Date:  2000-08       Impact factor: 9.031

Review 7.  The hypothalamic-pituitary-thyroid axis in infants and children: protection from radioiodines.

Authors:  Jeffrey Fisher; Xiaoxia Yang; Curtis Harris; Igor Koturbash; Annie Lumen
Journal:  J Thyroid Res       Date:  2014-05-25
  7 in total

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