Literature DB >> 1398381

Sudden unexpected death due to Taxus poisoning. A report of five cases, with review of the literature.

G Van Ingen1, R Visser, H Peltenburg, A M Van Der Ark, M Voortman.   

Abstract

The toxicity of yew (Taxus) has been known since antiquity. However, in the past 31 years, to our knowledge only six cases of Taxus poisoning have been reported in the literature. In the present paper we add five cases. From a forensic point of view, intoxication with Taxus has three important aspects: (i) the clinical presentation, which among other causes should suggest Taxus intoxication; (ii) the fact that the diagnosis may often be easily made by examination of the contents of stomach, duodenum and small bowel and (iii) the widespread availability in the near future of Taxol, an anti-neoplastic drug which is an alkaloid extracted from Taxus. The clinical and autopsy findings are summarized, the diagnostic aspects are discussed and the literature concerning Taxus is reviewed.

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Year:  1992        PMID: 1398381     DOI: 10.1016/0379-0738(92)90150-u

Source DB:  PubMed          Journal:  Forensic Sci Int        ISSN: 0379-0738            Impact factor:   2.395


  5 in total

1.  Quantitative determination of taxine B in body fluids by LC-MS-MS.

Authors:  L Frommherz; P Kintz; H Kijewski; H Köhler; M Lehr; B Brinkmann; J Beike
Journal:  Int J Legal Med       Date:  2006-01-06       Impact factor: 2.686

2.  A comparative study of five fatal cases of Taxus poisoning.

Authors:  J Pietsch; K Schulz; U Schmidt; H Andresen; B Schwarze; J Dressler
Journal:  Int J Legal Med       Date:  2006-05-06       Impact factor: 2.686

3.  LC-MS determination of Taxus alkaloids in biological specimens.

Authors:  J Beike; B Karger; T Meiners; B Brinkmann; H Köhler
Journal:  Int J Legal Med       Date:  2003-10-03       Impact factor: 2.686

4.  Fatal heart block from intentional yew tree (Taxus baccata) ingestion: a case report.

Authors:  Natasha G; Mark Chan; Ying X Gue; Diana A Gorog
Journal:  Eur Heart J Case Rep       Date:  2019-12-23

5.  A fatal case of Taxus poisoning.

Authors:  Sebastian Tranca; Cristina Laura Petrisor
Journal:  Clujul Med       Date:  2013-08-05
  5 in total

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