Literature DB >> 1398261

Effect of testosterone on the development of bladder tumors and calculi in female rats.

S Terada1, N Suzuki, K Uchide, K Akasofu, E Nishida.   

Abstract

In order to study the effect of testosterone on bladder calculi and tumor formation in female rats, Wistar rats were administered testosterone for 12, 18 or 24 weeks. Testosterone was found to increase the incidence of both bladder calculi and tumors in intact, but not in oophorectomized rats. It is suggested that testosterone in combination with estrogen may contribute to hyperplasia formation, in turn leading to an increased incidence of bladder calculi and tumors.

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Year:  1992        PMID： 1398261     DOI： 10.1159/000292737

Source DB:  PubMed          Journal:  Gynecol Obstet Invest        ISSN： 0378-7346            Impact factor:   2.031


  5 in total

Review 1.  Role of androgen receptor expression in non-muscle-invasive bladder cancer: a systematic review and meta-analysis.

Authors:  Francesca Sanguedolce; Luigi Cormio; Giuseppe Carrieri; Beppe Calò; Davide Russo; Andrea Menin; Antonio Luigi Pastore; Francesco Greco; Giorgio Bozzini; Antonio Galfano; Giovannalberto Pini; Angelo Porreca; Filippo Mugavero; Mario Falsaperla; Carlo Ceruti; Luca Cindolo; Alessandro Antonelli; Andrea Minervini
Journal:  Histol Histopathol       Date:  2019-12-05       Impact factor: 2.303

2.  The effect of androgen deprivation treatment on subsequent risk of bladder cancer diagnosis in male patients treated for prostate cancer.

Authors:  Marco Moschini; Emanuele Zaffuto; Pierre Karakiewicz; Agostino Mattei; Giorgio Gandaglia; Nicola Fossati; Francesco Montorsi; Alberto Briganti; Shahrokh F Shariat
Journal:  World J Urol       Date:  2018-10-01       Impact factor: 4.226

3.  DNA damage in exfoliated cells and histopathological alterations in the urinary tract of mice exposed to cigarette smoke and treated with chemopreventive agents.

Authors:  Sebastiano La Maestra; Rosanna T Micale; Silvio De Flora; Francesco D'Agostini; Gancho Ganchev; Marietta Iltcheva; Nikolay Petkov; Vernon E Steele; Roumen Balansky
Journal:  Carcinogenesis       Date:  2012-10-05       Impact factor: 4.944

4.  Depletion of androgen receptor low molecular weight isoform reduces bladder tumor cell viability and induces apoptosis.

Authors:  Kimberley Katleba; Alan P Lombard; Maria-Malvina Tsamouri; Han Bit Baek; Kristine S Nishida; Stephen J Libertini; Alexander J Platero; Ai-Hong Ma; Chong-Xian Pan; Paramita M Ghosh; Maria Mudryj
Journal:  Cancer Lett       Date:  2021-02-04       Impact factor: 8.679

Review 5.  Effects of Androgen and Estrogen Receptor Signaling Pathways on Bladder Cancer Initiation and Progression.

Authors:  Guilherme Godoy; Georgios Gakis; Carolyn L Smith; Omar Fahmy
Journal:  Bladder Cancer       Date:  2016-04-27
  5 in total

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