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Literature DB >> 1398228

Gastric mucosal barrier: barrier to hydrogen ions imparted by gastric surfactant in vitro.

Abstract

A simple experiment is described which shows how the highly surface active ingredient of gastric surfactant (DPPC) can be deposited on a filter paper to reduce the rate of transmission of hydrogen ions by one to two orders of magnitude. This finding is compatible with previous studies implying that the hydrophobic layer of surface active phospholipid provides the gastric mucosal barrier as a distinct physical entity.

Entities: Chemical

Mesh：

Substances：

Year: 1992 PMID： 1398228 PMCID： PMC1379438 DOI： 10.1136/gut.33.8.1039

Source DB: PubMed Journal: Gut ISSN： 0017-5749 Impact factor: 23.059

10 in total

1. FUNCTIONAL SIGNIFICANCE OF GASTRIC MUCOSAL BARRIER TO SODIUM.

Authors: H W DAVENPORT; H A WARNER; C F CODE
Journal: Gastroenterology Date: 1964-08 Impact factor: 22.682

2. Exogenous surface-active phospholipid protects Necturus gastric mucosa against luminal acid and barrier-breaking agents.

Authors: T Kiviluoto; H Paimela; H Mustonen; E Kivilaakso
Journal: Gastroenterology Date: 1991-01 Impact factor: 22.682

3. A physical identity for the gastric mucosal barrier.

Authors: B A Hills
Journal: Med J Aust Date: 1990-07-16 Impact factor: 7.738

4. What is the true role of surfactant in the lung?

Authors: B A Hills
Journal: Thorax Date: 1981-01 Impact factor: 9.139

5. Cytoprotective role of gastric surfactant in the ethanol-produced gastric mucosal injury of the rat.

Authors: I Szelenyi; H Engler
Journal: Pharmacology Date: 1986 Impact factor: 2.547

6. Protective effect of exogenous phospholipid on aspirin-induced gastric mucosal injury.

Authors: R A Swarm; S W Ashley; D I Soybel; F S Ordway; L Y Cheung
Journal: Am J Surg Date: 1987-01 Impact factor: 2.565

7. Molecular species of phosphatidylcholine from rat gastric mucosa.

Authors: M K Wassef; Y N Lin; M I Horowitz
Journal: Biochim Biophys Acta Date: 1979-04-27

8. Surface hydrophobicity of gastric mucosa in peptic ulcer disease. Relationship to gastritis and Campylobacter pylori infection.

Authors: R T Spychal; P M Goggin; J M Marrero; S H Saverymuttu; C W Yu; C M Corbishley; J D Maxwell; T C Northfield
Journal: Gastroenterology Date: 1990-05 Impact factor: 22.682

9. Surfactant approach to the gastric mucosal barrier: protection of rats by banana even when acidified.

Authors: B A Hills; C A Kirwood
Journal: Gastroenterology Date: 1989-08 Impact factor: 22.682

10. The fluid mosaic model of the structure of cell membranes.

Authors: S J Singer; G L Nicolson
Journal: Science Date: 1972-02-18 Impact factor: 47.728

10 in total

6 in total

5. A direct role for secretory phospholipase A2 and lysophosphatidylcholine in the mediation of LPS-induced gastric injury.

Authors: Elizabeth J Dial; Duy M Tran; Jimmy J Romero; Mayssa Zayat; Lenard M Lichtenberger
Journal: Shock Date: 2010-06 Impact factor: 3.454

6. Gastric mucosal barrier: evidence for Helicobacter pylori ingesting gastric surfactant and deriving protection from it.

Authors: B A Hills
Journal: Gut Date: 1993-05 Impact factor: 23.059