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Literature DB >> 1397209

DNA relatedness, karyotyping and gene probing of Candida tropicalis, Candida albicans and its synonyms Candida stellatoidea and Candida claussenii.

M Mahrous¹, A D Sawant, W R Pruitt, T Lott, S A Meyer, D G Ahearn.

Abstract

Isolates of Candida albicans with varied phenotypes, including sucrose-negative variants (C. stellatoidea, serotypes A and B) and avirulent germ tube-negative forms (C. claussenii) showed significant (greater than 90%) DNA relatedness to classical C. albicans, but insignificant relatedness to C. tropicalis and sucrose-negative C. tropicalis. A transverse alternating-field gel electrophoresis procedure (TAFE) showed discrete karyotype patterns among the phenotypic variants of C. albicans including the sucrose-negative C. stellatoidea. The number of chromosome-sized DNA bands for C. tropicalis (7 bands) were within the range of bands observed for C. albicans (5 to 10 bands). The general DNA-migration pattern for C. albicans appeared distinct from that of C. tropicalis. An aspartyl proteinase (PrA) gene probe from C. albicans hybridized with chromosomal DNA from C. albicans, C. claussenii and C. stellatoidea but not with that from C. tropicalis.

Entities: Chemical Disease Species

Mesh：

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Year: 1992 PMID： 1397209 DOI： 10.1007/bf00158581

Source DB: PubMed Journal: Eur J Epidemiol ISSN： 0393-2990 Impact factor: 8.082

30 in total

2. Characterization of agglutinin-like sequence genes from non-albicans Candida and phylogenetic analysis of the ALS family.

Authors: L L Hoyer; R Fundyga; J E Hecht; J C Kapteyn; F M Klis; J Arnold
Journal: Genetics Date: 2001-04 Impact factor: 4.562

3. Characterization of genetically distinct subgroup of Candida albicans strains isolated from oral cavities of patients infected with human immunodeficiency virus.

Authors: M McCullough; B Ross; P Reade
Journal: J Clin Microbiol Date: 1995-03 Impact factor: 5.948

3 in total

DNA relatedness, karyotyping and gene probing of Candida tropicalis, Candida albicans and its synonyms Candida stellatoidea and Candida claussenii.

1. Chromosomal rearrangement in Candida stellatoidea results in a positive effect on phenotype.

2. Characterization of atypical Candida tropicalis and other uncommon clinical yeast isolates.

3. A study of 666 strains of Candida albicans: correlation between serotype and susceptibility to 5-fluorocytosine.

4. Germ-tube formation by atypical strains of Candida albicans.

5. A reevaluation of the genus Malassezia by means of genome comparison.

6. Telomeric and dispersed repeat sequences in Candida yeasts and their use in strain identification.

7. Antigenic studies of Candida. I. Observation of two antigenic groups in Candida albicans.

8. Gastrointestinal and systemic candidosis in immunocompromised mice.

9. A comparison of secretory proteinases from different strains of Candida albicans.

10. Protein and enzyme electrophoresis profiles of selected Candida species.

1. Internal transcribed spacer sequencing versus biochemical profiling for identification of medically important yeasts.

2. Characterization of agglutinin-like sequence genes from non-albicans Candida and phylogenetic analysis of the ALS family.

3. Characterization of genetically distinct subgroup of Candida albicans strains isolated from oral cavities of patients infected with human immunodeficiency virus.