Literature DB >> 13967244

Hypersensitivity to a synthetic polypeptide: induction of a delayed reaction.

S BEN-EFRAIM, S FUCHS, M SELA.   

Abstract

A multichain copolypeptide, p(Tyr,Glu)-pAla--pLys, induced in guinea pigs a prolonged state of delayed hypersensitivity not associated with detectable circulating antibodies. Cross reactions of the delayed type were observed with chemically related polypeptides.

Entities:  

Keywords:  ANTIGEN-ANTIBODY REACTIONS; PEPTIDES

Mesh:

Substances:

Year:  1963        PMID: 13967244     DOI: 10.1126/science.139.3560.1222

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  3 in total

1.  Differences in immune response to synthetic antigens in two inbred strains of guinea-pigs.

Authors:  S Ben-Efraim; S Fuchs; M Sela
Journal:  Immunology       Date:  1967-05       Impact factor: 7.397

2.  Studies on the types of immune responses to synthetic antigens in guinea-pigs.

Authors:  Y Stupp; F Borek; M Sela
Journal:  Immunology       Date:  1966-12       Impact factor: 7.397

3.  Relation between optical configuration and immunogenicity of synthetic polypeptides.

Authors:  F Borek; Y Stupp; S Fuchs; M Sela
Journal:  Biochem J       Date:  1965-09       Impact factor: 3.857

  3 in total

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