Literature DB >> 13967189

The future of the diabetic child.

M M BELMONTE.   

Abstract

The favourable immediate prognosis that can be offered to the newly diabetic child of today is in contrast to the prognosis in the pre-insulin era. Nonetheless, the fact that vascular complications occur after a relatively few years of the disease point to deficiencies in our understanding of the disease and possibly to errors in our treatment. Current concepts of the etiology of these sequelae and their relation to past control are examined and lead to the conclusion that while vascular disease is probably inherent in the diabetic state, the degree of damage and the consequent loss of function can be modified to some degree at least by maintenance of good control. In this respect the role of serum lipids and the dietary fat content are reviewed but definitive conclusions seem unwarranted. Oral hypoglycemic agents have been shown to have little or no place in the treatment of juvenile diabetics. Continued careful observation of diabetic patients in addition to basic research is needed to improve our understanding and management of this disease.

Entities:  

Keywords:  DIABETES MELLITUS, JUVENILE

Mesh:

Substances:

Year:  1963        PMID: 13967189      PMCID: PMC1921432     

Source DB:  PubMed          Journal:  Can Med Assoc J        ISSN: 0008-4409            Impact factor:   8.262


  17 in total

1.  Retinopathy and neuropathy in one hundred growth-onset diabetic patients.

Authors:  R T COLLYER; B E HAZLETT
Journal:  Can Med Assoc J       Date:  1961-12-16       Impact factor: 8.262

2.  Childhood diabetes. Its course, and influence on the second and third generations.

Authors:  P WHITE
Journal:  Diabetes       Date:  1960 Sep-Oct       Impact factor: 9.461

3.  Plasma insulin concentrations in nondiabetic and early diabetic subjects. Determinations by a new sensitive immuno-assay technic.

Authors:  R S YALOW; S A BERSON
Journal:  Diabetes       Date:  1960 Jul-Aug       Impact factor: 9.461

4.  Histology of small blood vessel disease in diabetes.

Authors:  A R COLWELL
Journal:  Diabetes       Date:  1960 Nov-Dec       Impact factor: 9.461

5.  Defective synthesis of triglyceride fatty acids from 1-C-14 acetate in the well-controlled stable adult diabetic.

Authors:  A R HENNES; T W REDDING
Journal:  Diabetes       Date:  1961 Mar-Apr       Impact factor: 9.461

6.  Actions of phenethylbiguanide and related compounds.

Authors:  D F STEINER; R H WILLIAMS
Journal:  Diabetes       Date:  1959 Mar-Apr       Impact factor: 9.461

7.  Symposium on "a new oral hypoglycemic agent, phenformin (DBI)": general summary.

Authors:  A MARBLE
Journal:  Diabetes       Date:  1960 May-Jun       Impact factor: 9.461

8.  Serum triglycerides in health and diabetes.

Authors:  M J ALBRINK; E B MAN
Journal:  Diabetes       Date:  1958 May-Jun       Impact factor: 9.461

9.  Angioscopic changes in the smaller blood vessels in diabetes mellitus and their relationship to aging.

Authors:  J DITZEL
Journal:  Circulation       Date:  1956-09       Impact factor: 29.690

10.  Mechanistic basis for the selection of hypoglycemic therapies.

Authors:  H S SADOW
Journal:  Appl Ther       Date:  1962-04
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  1 in total

Review 1.  100 years on: the impact of the discovery of insulin on clinical outcomes.

Authors:  John B Buse; Melanie J Davies; Brian M Frier; Athena Philis-Tsimikas
Journal:  BMJ Open Diabetes Res Care       Date:  2021-08
  1 in total

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