Literature DB >> 13965169

Effect of chlorpromazine, reserpine, benactyzine and phenobarbitone on the release of corticotrophin in the rat.

A ASHFORD, M SHAPERO.   

Abstract

A single injection into the rat of chlorpromazine, reserpine, benactyzine or phenobarbitone stimulates the release of corticotrophin. This effect is not seen after the drugs have been injected daily for 5 days, nor when the rats are hypophysectomized or pretreated with hydrocortisone. The stimulant effect of ether on corticotrophin release is not modified by pretreatment with a single injection, nor to any great extent after 5 daily injections of these drugs.

Entities:  

Keywords:  ASCORBIC ACID; BENACTYZINE; CHLORPROMAZINE; CORTICOTROPIN; PHENOBARBITAL; RESERPINE

Mesh：

Substances：

Year:  1962        PMID： 13965169      PMCID： PMC1482213          DOI： 10.1111/j.1476-5381.1962.tb01450.x

Source DB:  PubMed          Journal:  Br J Pharmacol Chemother        ISSN： 0366-0826


  12 in total

1.  Endocrine pharmacology.

Authors:  R GAUNT; J J CHART; A A RENZI
Journal:  Science       Date:  1961-03-03       Impact factor: 47.728

2.  Depletion of pituitary corticotrophin by reserpine and by a nitrogen mustard.

Authors:  M SAFFRAN; M VOGT
Journal:  Br J Pharmacol Chemother       Date:  1960-03

3.  Effect of chlorpromazine on stress induced adrenal ascorbic acid depletion.

Authors:  R W SEVY; E A OHLER; A WEINER
Journal:  Endocrinology       Date:  1957-07       Impact factor: 4.736

4.  The effect of certain central nervous system depressants on pituitary-adrenal activating agents.

Authors:  P F D VAN PEENEN; E L WAY
Journal:  J Pharmacol Exp Ther       Date:  1957-06       Impact factor: 4.030

5.  The effect of reserpine and chlorpromazine on the response of the rat to acute stress.

Authors:  M MAHFOUZ; E A EZZ
Journal:  J Pharmacol Exp Ther       Date:  1958-05       Impact factor: 4.030

6.  The inhibitory effect of reserpine on ACTH secretion in response to stressful stimuli.

Authors:  F N BRIGGS; P L MUNSON; H WELLS
Journal:  Endocrinology       Date:  1956-11       Impact factor: 4.736

7.  Inhibition of the release of corticotrophin from the hypophysis by chlorpromazine.

Authors:  C C OLLING; D DE WIED
Journal:  Acta Endocrinol (Copenh)       Date:  1956-07

8.  Blood ACTH in the stressed adrenalectomized rat after intravenous injection of hydrocortisone.

Authors:  K L SYDNOR
Journal:  Endocrinology       Date:  1955-02       Impact factor: 4.736

9.  The action of chlorpromazine on diencephalic sympathetic activity and on the release of adrenocorticotrophic hormone.

Authors:  M HOLZBAUER; M VOGT
Journal:  Br J Pharmacol Chemother       Date:  1954-12

10.  Effect of plasma from hypophyseal-portal vessel blood on adrenal ascorbic acid.

Authors:  J C PORTER; J C JONES
Journal:  Endocrinology       Date:  1956-01       Impact factor: 4.736
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  1 in total

1.  Modification of stress responses in histamine-depleted rats.

Authors:  W F Bousquet; T S Miya; C Sanchez
Journal:  Br J Pharmacol Chemother       Date:  1966-05
  1 in total

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