Literature DB >> 1396452

The effect of gamma-irradiation on the adherent capacity and iron metabolism of alveolar macrophages in mice and rats.

Y Kubota1, H Sato, S Takahashi.   

Abstract

The effect of external gamma-irradiation on the survival of alveolar macrophages (AM) and on the extracellular release of 59Fe from AM-ingested [59Fe]iron hydroxide colloid was investigated in vitro using cells from C3H mice and Wistar rats. 59Fe release from mouse AM was enhanced by irradiation in a dose-dependent fashion, but irradiation up to 112 Gy did not affect the release from rat AM. Cell survival of AM, measured by direct counting of cell nuclei of adherent AM or vital staining with crystal violet, decreased dose dependently in mice and rats, but mouse AM were more radiosensitive than rat AM.

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Year:  1992        PMID: 1396452      PMCID: PMC1519562          DOI: 10.1289/ehp.9297163

Source DB:  PubMed          Journal:  Environ Health Perspect        ISSN: 0091-6765            Impact factor:   9.031


  5 in total

1.  The effect of external gamma-irradiation on 59Fe release in vitro from alveolar macrophages previously having ingested 59Fe-iron hydroxide colloid.

Authors:  S Takahashi; Y Kubota; H Sato
Journal:  J Radiat Res       Date:  1990-09       Impact factor: 2.724

2.  A comparative study of superoxide dismutase activity in polymorphonuclear leukocytes, monocytes, and alveolar macrophages of the guinea pig.

Authors:  M Rister; R L Baehner
Journal:  J Cell Physiol       Date:  1976-03       Impact factor: 6.384

3.  Radiosensitivity of pulmonary alveolar macrophage colony-forming cells.

Authors:  H S Lin; C Kuhn; D M Chen
Journal:  Radiat Res       Date:  1982-02       Impact factor: 2.841

4.  Purification and physico-chemical characterization of rabbit tumor necrosis factor.

Authors:  M R Ruff; G E Gifford
Journal:  J Immunol       Date:  1980-10       Impact factor: 5.422

5.  The role of oxygen-derived free radicals in radiation-induced damage and death of nondividing eucaryotic cells.

Authors:  G McLennan; L W Oberley; A P Autor
Journal:  Radiat Res       Date:  1980-10       Impact factor: 2.841

  5 in total

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