Literature DB >> 1395879

[Treatment of pilonidal sinus with excision and primary suture using a local, resorbable antibiotic carrier. Results of a prospective randomized study].

P Vogel1, J Lenz.   

Abstract

The excision of a pilonidal sinus with wound healing by second intention, often results in a long duration of treatment. On the other hand, primary suture after excision has a high rate of abscess formation. In a randomized study we treated 40 patients with excision of pilonidal sinus, insertion of a collagen sponge containing Gentamicin and primary suture (group 1) to prevent this abscess formation. Another 40 patients were treated in the same way but without applying the Gentamicin-collagen sponge (group 2). There had been no significant differences as to the history and duration of the disease, the wound size, the degree of inflammation, the weight of the patients or the amount of hair near the sinus. In group 1 only 7.5% of the patients had a postoperative abscess formation, in contrast to group 2, with an abscess rate of 52.5% and consecutive surgery (p less than 0.001). One year after the operation the recurrence rate was 0 in both groups. Considering the results mentioned, surgical excision of the pilonidal sinus in combination with insertion of a resorbable antibiotic sponge we recommend this therapy.

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Year:  1992        PMID: 1395879

Source DB:  PubMed          Journal:  Chirurg        ISSN: 0009-4722            Impact factor:   0.955


  14 in total

1.  The treatment of pilonidal disease: guidelines of the Italian Society of Colorectal Surgery (SICCR).

Authors:  D Segre; M Pozzo; R Perinotti; B Roche
Journal:  Tech Coloproctol       Date:  2015-09-16       Impact factor: 3.781

2.  [Wound care management of ulceration in a palliative care patient].

Authors:  Franz Reiner
Journal:  Wien Med Wochenschr       Date:  2006-05

3.  Microbiology of the infected recurrent sacrococcygeal pilonidal sinus.

Authors:  Michael Ardelt; Yves Dittmar; Roland Kocijan; Jürgen Rödel; Birte Schulz; Hubert Scheuerlein; Utz Settmacher
Journal:  Int Wound J       Date:  2014-04-24       Impact factor: 3.315

Review 4.  Antimicrobials as an adjunct to pilonidal disease surgery: a systematic review of the literature.

Authors:  M N Mavros; P K Mitsikostas; V G Alexiou; G Peppas; M E Falagas
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2013-02-05       Impact factor: 3.267

5.  Local administration of antibiotics by gentamicin-collagen sponge does not improve wound healing or reduce recurrence rate after pilonidal excision with primary suture: a prospective randomized controlled trial.

Authors:  Roland E Andersson; Gudrun Lukas; Stefan Skullman; Anders Hugander
Journal:  World J Surg       Date:  2010-12       Impact factor: 3.352

6.  What is the role of mechanical bowel preparation in patients with pilonidal sinus undergoing surgery? Prospective, randomized, surgeon-blinded trial.

Authors:  Cem Terzi; Aras Emre Canda; Tarkan Unek; Esra Dalgic; Mehmet Fuzun
Journal:  World J Surg       Date:  2005-11       Impact factor: 3.352

Review 7.  Local application of gentamicin collagen implants in the prophylaxis of surgical site infections following gastrointestinal surgery: a review of clinical experience.

Authors:  A F J de Bruin; M P Gosselink; E van der Harst; H J T Rutten
Journal:  Tech Coloproctol       Date:  2010-06-29       Impact factor: 3.781

8.  A prospective randomised study comparing two treatment modalities for chronic pilonidal sinus with a 5-year follow-up.

Authors:  Milind M Rao; Wojtek Zawislak; Raymond Kennedy; Robert Gilliland
Journal:  Int J Colorectal Dis       Date:  2009-10-13       Impact factor: 2.571

9.  Delayed wound healing in sacrococcygeal pilonidal sinus coincides with an altered collagen composition.

Authors:  Marcel Binnebösel; Karsten Junge; Robert Schwab; Albert Antony; Volker Schumpelick; Uwe Klinge
Journal:  World J Surg       Date:  2009-01       Impact factor: 3.352

Review 10.  Local administration of gentamicin collagen sponge in surgical excision of sacrococcygeal pilonidal sinus disease: a systematic review and meta-analysis of the literature.

Authors:  A L Nguyen; A A Pronk; E J B Furnée; A Pronk; P H P Davids; N Smakman
Journal:  Tech Coloproctol       Date:  2015-11-06       Impact factor: 3.781

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