Literature DB >> 13956520

A psychiatric and psychological study of amitriptyline (Elavil) as an antidepressant.

J INGLIS, R P JONES, R B SLOANE.   

Abstract

The antidepressant effects of amitriptyline (Elavil) were investigated by means of psychiatric assessment and psychological testing of 20 depressed patients who were compared, before and after treatment, with a placebo-treated control group of 14 similar patients. After three weeks on doses of 150 mg. per day, 13 out of 20 of the actively treated group were rated as improved, compared with only three out of 11 of the control group (p < .05). Clinical improvement was associated with changes on some objective tests. No persistent adverse side effects were observed. It was concluded that amitriptyline is an effective antidepressant.

Entities:  

Keywords:  NEUROSES; PSYCHOSES, MANIC-DEPRESSIVE

Mesh:

Substances:

Year:  1963        PMID: 13956520      PMCID: PMC1921342     

Source DB:  PubMed          Journal:  Can Med Assoc J        ISSN: 0008-4409            Impact factor:   8.262


  13 in total

1.  [Treatment of endogenous depression with amitryptyline].

Authors:  O H ARNOLD; G FOITL
Journal:  Wien Med Wochenschr       Date:  1961-04-22

2.  [Amitryptyline (Saroten), a new antidepressive agent].

Authors:  H BRATLUND; L S STROMGREN
Journal:  Ugeskr Laeger       Date:  1961-09-15

3.  An objective assessment of the effects of nialamide on depressed patients.

Authors:  J INGLIS; W K CAIRD; R B SLOANE
Journal:  Can Med Assoc J       Date:  1961-05-13       Impact factor: 8.262

4.  The antidepresant qualities of Elavil.

Authors:  E DUNLOP
Journal:  Dis Nerv Syst       Date:  1961-04

5.  Hospitalized depressions. Drugs or electrotherapy?

Authors:  A S NORRIS; J CLANCY
Journal:  Arch Gen Psychiatry       Date:  1961-09

6.  [Clinical experiences with the dibenzocycloheptadiene derivative amitriptyline (Ro 4-1575) in psychiatric patients].

Authors:  H GROSS; E KALTENBAECK
Journal:  Wien Med Wochenschr       Date:  1961-04-15

7.  On the parenteral use of amitriptyline (ElavilMerck): a preliminary report.

Authors:  H FREED
Journal:  Am J Psychiatry       Date:  1960-11       Impact factor: 18.112

8.  Experiences with Elavil: treatment of fifty-one cases of depression.

Authors:  M D PRESSMAN; L B WEISS
Journal:  Am J Psychiatry       Date:  1961-07       Impact factor: 18.112

9.  Amitriptyline in the treatment of alcoholics: a pilot study.

Authors:  Y MAWARDI; K S DITMAN; H B MOONEY
Journal:  J Obstet Gynaecol Br Emp       Date:  1961 May-Jun

10.  Some factors affecting reaction times to auditory stimuli in mental patients.

Authors:  K R HALL; E STRIDE
Journal:  J Ment Sci       Date:  1954-04
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  1 in total

1.  [Poisoning with an antidepressive agent. Status epilepticus in suicidal amitriptyline intoxication. Remarks on the neurology of severe poisonings].

Authors:  C Scharfetter
Journal:  Arch Psychiatr Nervenkr (1970)       Date:  1965-09-08
  1 in total

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