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Literature DB >> 13952049

Tests for addiction (chronic intoxication) of morphine type.

Abstract

A survey is presented of laboratory and clinical methods for the determination of addiction liability of substances with morphine-like effects. Since physical dependence is the outstanding pharmacological criterion of addiction of morphine type, the procedures for its qualitative and quantitative assessment are described in detail.

Entities: Chemical

Keywords: DRUG ADDICTION; MORPHINE ADDICTION

Mesh：

Substances：
Morphine

Year: 1963 PMID： 13952049 PMCID： PMC2554465

Source DB: PubMed Journal: Bull World Health Organ ISSN： 0042-9686 Impact factor: 9.408

29 in total

1. [Semiquantitative determination of physical dependence in morphine and methadon therapy].

Authors: O SCHRAPPE; J M BURCHARD; K GEHLKEN
Journal: Arch Psychiatr Nervenkr Z Gesamte Neurol Psychiatr Date: 1959

2. Rapid identification of analgesic drugs in urine with thin-layer chromatography.

Authors: J COCHIN; J W DALY
Journal: Experientia Date: 1962-06-15

3. A demonstration of morphine tolerance and physical dependence in the rat.

Authors: C HANNA
Journal: Arch Int Pharmacodyn Ther Date: 1960-03-01

4. [Analgesic properties of four 2-aminomethyl-7-benzoyl-benzodioxans].

Authors: J JACOB; M BLOZOVSKI; P ECHINARDGARIN
Journal: Therapie Date: 1958 Impact factor: 2.070

5. Synthetic substances with morphine-like effect; relationship between analgesic action and addiction liability, with a discussion of the chemical structure of addiction-producing substances.

Authors: N B EDDY; H HALBACH; O J BRAENDEN
Journal: Bull World Health Organ Date: 1956 Impact factor: 9.408

6. Studies on the pharmacology of N-allylnormorphine.

Authors: C A WINTER; P D ORAHOVATS; L FLATAKER; E G LEHMAN; J T LEHMAN
Journal: J Pharmacol Exp Ther Date: 1954-06 Impact factor: 4.030

7. Effects of single doses of N-Allylnormorphine on hindlimb reflexes of chronic spinal dogs during cycles of morphine addiction.

Authors: A WIKLER; R L CARTER
Journal: J Pharmacol Exp Ther Date: 1953-09 Impact factor: 4.030

8. Hindlimb reflexes of chronic spinal dots during cycles of addiction to morphine and methadon.

Authors: A WIKLER; K FRANK
Journal: J Pharmacol Exp Ther Date: 1948-12 Impact factor: 4.030

9. Addiction liability of an isoquinoline analgesic, 1-(p-chlorophenethyl)-2-methyl-6,7-dimethoxy-1.2.3.4-tetrahydroisoquinoline.

Authors: H F FRASER; W R MARTIN; A B WOLBACH; H ISBELL
Journal: Clin Pharmacol Ther Date: 1961 May-Jun Impact factor: 6.875

10. The analgesic equivalence to morphine and relative side action liability of oxymorphone (14-hydroxydihydro morphinone).

Authors: N B EDDY; L E LEE
Journal: J Pharmacol Exp Ther Date: 1959-02 Impact factor: 4.030

8 in total

4. Prescribing narcotics to habitual and addicted narcotic users. Medical and legal guidelines in California and some other Western states.

Authors: F S Tennant; G F Uelmen
Journal: West J Med Date: 1980-12

Tests for addiction (chronic intoxication) of morphine type.

1. [Semiquantitative determination of physical dependence in morphine and methadon therapy].

2. Rapid identification of analgesic drugs in urine with thin-layer chromatography.

3. A demonstration of morphine tolerance and physical dependence in the rat.

4. [Analgesic properties of four 2-aminomethyl-7-benzoyl-benzodioxans].

5. Synthetic substances with morphine-like effect; relationship between analgesic action and addiction liability, with a discussion of the chemical structure of addiction-producing substances.

6. Studies on the pharmacology of N-allylnormorphine.

7. Effects of single doses of N-Allylnormorphine on hindlimb reflexes of chronic spinal dogs during cycles of morphine addiction.

8. Hindlimb reflexes of chronic spinal dots during cycles of addiction to morphine and methadon.

9. Addiction liability of an isoquinoline analgesic, 1-(p-chlorophenethyl)-2-methyl-6,7-dimethoxy-1.2.3.4-tetrahydroisoquinoline.

10. The analgesic equivalence to morphine and relative side action liability of oxymorphone (14-hydroxydihydro morphinone).

1. DRUG ADDICTION. PHARMACOLOGICAL ASPECTS OF ADDICTION TO MORPHINE AND OTHER DRUGS.

2. The induction of physical dependence to morphine in the rat using a subcutaneously implanted reservoir.

3. Assessment of morphine-type physical dependence liability: a screening method using the rat.

4. Prescribing narcotics to habitual and addicted narcotic users. Medical and legal guidelines in California and some other Western states.

5. An implanted reservoir of morphine solution for rapid induction of physical dependence in rats.

6. The effect of compound 48/80 on the precipitated withdrawal syndrome of dogs.

7. Pharmacological characterization of opiate physical dependence in the isolated ileum of the guinea-pig.

8. Drug dependence: its significance and characteristics.