Literature DB >> 13950185

Glycogen deposition in the liver induced by cortisone: dependence on enzyme synthesis.

O GREENGARD, G WEBER, R L SINGHAL.   

Abstract

The deposition of liver glycogen in starved rats given a single dose of cortisone is inhibited by puromycin and actinomycin. The former agent interferes with induced enzyme formation in general, and the latter with the cortisone-induced rise in liver enzyme levels. The results suggest that the regulatory eJffect of cortisone on carbohydrate metabolism may be brought about -by its action on the cellular concentration of certain enzyme proteins.

Entities:  

Keywords:  AMINOTRANSFERASES; CORTISONE; LIVER GLYCOGEN

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Substances:

Year:  1963        PMID: 13950185     DOI: 10.1126/science.141.3576.160-a

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  3 in total

1.  ON THE MECHANISM OF ACTION OF ALDOSTERONE ON SODIUM TRANSPORT: THE ROLE OF PROTEIN SYNTHESIS.

Authors:  I S EDELMAN; R BOGOROCH; G A PORTER
Journal:  Proc Natl Acad Sci U S A       Date:  1963-12       Impact factor: 11.205

2.  [Glucose tolerance testing after intravenous betamethasone phosphate, with concomitant uric acid and cholesterol analyses. A reassessment of both glucocorticoid and afternoon testing in "early chemical diabetes"].

Authors:  H J Roberts
Journal:  Acta Diabetol Lat       Date:  1971 May-Jun

3.  EFFECTS OF BACTERIAL ENDOTOXINS ON METABOLISM. VII. ENZYME INDUCTION AND CORTISONE PROTECTION.

Authors:  L J BERRY; D S SMYTHE
Journal:  J Exp Med       Date:  1964-11-01       Impact factor: 14.307

  3 in total

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