Literature DB >> 13946281

Generalized Shwartzman reaction in the pregnant golden hamster.

M GALTON.   

Abstract

A single intraperitoneal injection of colchicine regularly elicits the generalized Shwartzman phenomenon in the pregnant golden hamster. Non-pregnant hamsters are refractory both to colchicine and endotoxin. The superiority of colchicine, as opposed to foreign endotoxin, in the pregnant subject, may be attributed to the action of native endotoxin which is allowed parenteral access as a result of colchicine-induced injury to the intestinal mucosa.

Entities:  

Keywords:  COLCHICINE; PREGNANCY, ANIMAL; SHWARTZMAN PHENOMENON

Mesh：

Substances：

Year:  1963        PMID： 13946281     DOI： 10.1126/science.139.3558.923

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  5 in total

1.  Failure of bacterial endotoxin to produce the generalized Shwartzman reaction in the Syrian hamster.

Authors:  K Merritt; M Galton
Journal:  J Bacteriol       Date:  1967-09       Impact factor: 3.490

2.  Fibrinogen deposition in acute renal failure.

Authors:  D Koffler; F Paronetto
Journal:  Am J Pathol       Date:  1966-08       Impact factor: 4.307

3.  Role of the acute phase response in the Shwartzman phenomenon.

Authors:  M B Pepys; S L Rogers; D J Evans
Journal:  Clin Exp Immunol       Date:  1982-02       Impact factor: 4.330

4.  Adjuvant action of bacterial endotoxin and colchicine on antibody formation in the hamster.

Authors:  K Merritt
Journal:  Infect Immun       Date:  1971-10       Impact factor: 3.441

5.  Studies of the generalized Shwartzman reaction in the pregnant golden hamster.

Authors:  M Galton
Journal:  Am J Pathol       Date:  1964-04       Impact factor: 4.307
  5 in total

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