Literature DB >> 13942352

The relation between urogastrone and gonadotrophins.

B A PERERA, V M ROSENOER.   

Abstract

A commercial preparation of chorionic gonadotrophin inhibited gastric acid secretion induced by carbachol in rats. When the preparation was incubated for 10 min at 100 degrees C and pH 7, its gonadotrophic activity, as measured by a simple quantal assay based on the male toad spermiation response, was reduced by 92%. The inhibition of gastric acid secretion by the preparation was not significantly reduced by this treatment. It is concluded that the two activities are separable.

Entities:  

Keywords:  GASTRIC JUICE; GASTROINTESTINAL HORMONES; GONADOTROPINS, CHORIONIC

Mesh：

Substances：

Year:  1963        PMID： 13942352      PMCID： PMC1703801          DOI： 10.1111/j.1476-5381.1963.tb01490.x

Source DB:  PubMed          Journal:  Br J Pharmacol Chemother        ISSN： 0366-0826


  11 in total

1.  A gonadotropin-inhibiting substance in the urine of normal young children.

Authors:  L J SOFFER; W FUTTERWEIT; J SALVANESCHI
Journal:  J Clin Endocrinol Metab       Date:  1961-10       Impact factor: 5.958

2.  Inhibition of acid gastric secretion in the rat by chorionic gonadotrophin.

Authors:  M N GHOSH
Journal:  J Physiol       Date:  1959-10       Impact factor: 5.182

3.  Studies on urinary gonadotrophins I. Large scale preparation of highly active gonadotrophins from the urine of postmenopausal women.

Authors:  S G JOHNSEN
Journal:  Acta Endocrinol (Copenh)       Date:  1955-09

4.  The assay of urogastrone.

Authors:  V M ROSENOER; H O SCHILD
Journal:  J Physiol       Date:  1962-06       Impact factor: 5.182

5.  A method of conducting a biological assay on a preparation giving repeated graded responses illustrated by the estimation of histamine.

Authors:  H O Schild
Journal:  J Physiol       Date:  1942-06-02       Impact factor: 5.182

6.  INHIBITION OF GASTRIC SECRETION BY EXTRACTS OF NORMAL MALE URINE.

Authors:  J S Gray; E Wieczorowski; A C Ivy
Journal:  Science       Date:  1939-05-26       Impact factor: 47.728

7.  The preparation of urogastrone.

Authors:  J L MONGAR; V M ROSENOER
Journal:  J Physiol       Date:  1962-06       Impact factor: 5.182

8.  The inhibition of gastric secretion; a review.

Authors:  C F CODE
Journal:  Pharmacol Rev       Date:  1951-03       Impact factor: 25.468

9.  The use of Xenopus laevis, Bufo bufo, and Rana esculenta as test animals for gonadotrophic hormones. III. Quantitative investigations on the sensitivity of the animals to chorionic gonadotrophin.

Authors:  J V THORBORG; K HANSEN
Journal:  Acta Endocrinol (Copenh)       Date:  1951

10.  The chemical nature of urogastrone.

Authors:  A N WICK; R MEDZ; E PECKA
Journal:  Arch Biochem       Date:  1949-11
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