Literature DB >> 13939069

Hepatic and cardiac necrosis in a patient with prostatic carcinoma given 6-aminocaproic acid.

F NOUR-ELDIN, T F DRAISEY.   

Abstract

The pathological findings in a case of prostatic carcinoma with fibrinolysin, treated with epsilon-aminocaproic acid, included hepatic and cardiac necrosis. The possibility is discussed that the latter lesions may be a complication of epsilon-aminocaproic acid therapy or produced by the proteolytic action of the fibrinolysin.

Entities:  

Keywords:  AMINO ACIDS; CAPROATES; FIBRINOLYSIN; HEART DISEASES; LIVER DISEASES; PROSTATIC NEOPLASMS

Mesh:

Substances:

Year:  1963        PMID: 13939069      PMCID: PMC480487          DOI: 10.1136/jcp.16.1.61

Source DB:  PubMed          Journal:  J Clin Pathol        ISSN: 0021-9746            Impact factor:   3.411


  8 in total

1.  Fibrinolysis and fibrinolytic activity in man.

Authors:  S SHERRY; A P FLETCHER; N ALKJAERSIG
Journal:  Physiol Rev       Date:  1959-04       Impact factor: 37.312

2.  Antifibrinolytic activity and metabolism of 6-aminocaproic acid in man.

Authors:  I M NILSSON; A SJOERDSMA; J WALDENSTROM
Journal:  Lancet       Date:  1960-06-18       Impact factor: 79.321

3.  The use of plasmin in the treatment of intravascular thromboses.

Authors:  E E CLIFFTON
Journal:  J Am Geriatr Soc       Date:  1958-02       Impact factor: 5.562

4.  The biological significance of fibrinolysis.

Authors:  T ASTRUP
Journal:  Lancet       Date:  1956-09-15       Impact factor: 79.321

5.  Factor 5 deficiency in hemorrhagic diathesis (parahemophilia).

Authors:  S W COSGRIFF; E LEIFER
Journal:  J Am Med Assoc       Date:  1952-02-09

6.  Activity of plasma labile factor in disease.

Authors:  M STEFANINI
Journal:  Lancet       Date:  1951-03-17       Impact factor: 79.321

7.  Formation of bradykinin in anaphylactic and peptone shock.

Authors:  W T BERALDO
Journal:  Am J Physiol       Date:  1950-11

8.  Clinical experiences with 6-aminocaproic acid (6-ACA) as an antifibrinolytic agent.

Authors:  I M NILSSON; S E BJORKMAN; L ANDERSSON
Journal:  Acta Med Scand       Date:  1961-10
  8 in total

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