Literature DB >> 13935529

Thyroxine: effects on amino acid incorporation into protein in vivo.

R MICHELS, J CASON, L SOKOLOFF.   

Abstract

Treatment of rats with L-thyroxine increases the incorporation in vivo of radioactive amino acids into protein of liver, kidney, and heart, but not of spleen, testis, or brain. The distribution of the effect among the organs is the same as that observed in thyroxine stimulation of oxidative metabolism. Thus, stimulation of protein synthesis seems to be a physiological action of the thyroid hormone.

Entities:  

Keywords:  PROTEIN METABOLISM; THYROXIN

Mesh:

Substances:

Year:  1963        PMID: 13935529     DOI: 10.1126/science.140.3574.1417

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  8 in total

1.  THYROXINE STIMULATION OF AMINO ACID INCORPORATION INTO PROTEIN INDEPENDENT OF ANY ACTION ON MESSENGER RNA SYNTHESIS.

Authors:  L SOKOLOFF; C M FRANCIS; P L CAMPBELL
Journal:  Proc Natl Acad Sci U S A       Date:  1964-09       Impact factor: 11.205

2.  Mechanisms of stimulation of protein synthesis by thyroid hormones in vivo.

Authors:  L Sokoloff; P A Roberts; M M Januska; J E Kline
Journal:  Proc Natl Acad Sci U S A       Date:  1968-06       Impact factor: 11.205

3.  Thyroid-hormone effects on ornithine decarboxylase.

Authors:  E W Chideckel; S J Rozovski; E R Belur
Journal:  Biochem J       Date:  1980-11-15       Impact factor: 3.857

4.  Additive effects of thyroid hormone, growth hormone and testosterone on deoxyribonucleic acid-dependent ribonucleic acid polymerase in rat-liver nuclei.

Authors:  C C Widnell; J R Tata
Journal:  Biochem J       Date:  1966-02       Impact factor: 3.857

5.  Ribonucleic acid synthesis during the early action of thyroid hormones.

Authors:  J R Tata; C C Widnell
Journal:  Biochem J       Date:  1966-02       Impact factor: 3.857

6.  The change of alanine-ketoglutaric transaminase activity on the effect of leucine in liver of rats treated with thyroxine.

Authors:  H H Mazarean
Journal:  Naturwissenschaften       Date:  1966-01

7.  The calcium pump of cardiac sarcoplasmic reticulum. Functional alterations at different levels of thyroid state in rabbits.

Authors:  J Suko
Journal:  J Physiol       Date:  1973-02       Impact factor: 5.182

8.  Conversion and binding of tetraiodothyronine in developing rat brain.

Authors:  T Valcana
Journal:  Neurochem Res       Date:  1981-07       Impact factor: 3.996

  8 in total

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