Literature DB >> 13935078

Serum uric acid in young mongoloids.

E T MERTZ, R W FULLER, J M CONCON.   

Abstract

A highly significant increase (P {lt} .005) in average uric acid level was found in the blood serum of 25 mongoloids in the age range of 2 to 12 years, with a mean age of 6 years, when levels were compared with those in nonmongoloid, mentally retarded children. These data confirm our previou results with 40 mongoloids whose mean age was 23.7 years, and indicate that elevated uric acid levels are present throughout most of the life of these subjects.

Entities:  

Keywords:  MONGOLISM; URIC ACID

Mesh：

Substances：

Year:  1963        PMID： 13935078     DOI： 10.1126/science.141.3580.535

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  5 in total

1.  QUANTITATIVE STUDIES ON A2, SICKLE CELL, AND FETAL HEMOGLOBINS IN NEGROES WITH MONGOLISM, WITH OBSERVATIONS ON TRANSLOCATION MONGOLISM IN NEGROES.

Authors:  E D WEINSTEIN; D L RUCKNAGEL; M W SHAW
Journal:  Am J Hum Genet       Date:  1965-09       Impact factor: 11.025

2.  Uric acid metabolism in two patients with coexistent Down's syndrome and gout.

Authors:  M L Ciompi; L M Bazzichi; D Bertolucci; M R Mazzoni; P Barbieri; S Mencacci; D Macchia; G Mariani
Journal:  Clin Rheumatol       Date:  1984-06       Impact factor: 2.980

3.  Synthesis and concentration of 5-phosphoribosyl-1-pyrophosphate in erythrocytes from patients with Down's syndrome.

Authors:  Y Nishida; I Akaoka; T Nishizawa; M Maruki; K Maruki
Journal:  Ann Rheum Dis       Date:  1977-06       Impact factor: 19.103

Review 4.  Meta-analysis of metabolites involved in bioenergetic pathways reveals a pseudohypoxic state in Down syndrome.

Authors:  Laszlo Pecze; Elisa B Randi; Csaba Szabo
Journal:  Mol Med       Date:  2020-11-09       Impact factor: 6.354

5.  Biochemical Discrimination of the Down Syndrome-Related Metabolic and Oxidative/Nitrosative Stress Alterations from the Physiologic Age-Related Changes through the Targeted Metabolomic Analysis of Serum.

Authors:  Giacomo Lazzarino; Angela M Amorini; Renata Mangione; Miriam Wissam Saab; Enrico Di Stasio; Michelino Di Rosa; Barbara Tavazzi; Giuseppe Lazzarino; Graziano Onder; Angelo Carfì
Journal:  Antioxidants (Basel)       Date:  2022-06-20
  5 in total

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