Literature DB >> 139320

Synaptosomal adenosine triphosphatase (ATPase) inhibition by organophosphates.

H R Brown, R P Sharma.   

Abstract

Chicken spinal cord adenosine triphosphatases (both Na+, K+ stimulated and ouabain insensitive) were inhibited by tri-o-tolyl phosphate (TOTP, a neurotoxic organophosphate which is not a cholinesterase inhibitor) and mevinphos (a non-neurotoxic compound but inhibitor of cholinesterases). The inhibition was concentration and time dependent, with an initial rapid drop in activity followed by a gradual exponential decline.

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Year:  1976        PMID： 139320     DOI： 10.1007/bf01924440

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  14 in total

1.  INHIBITION BY DIISOPROPYLFLUOROPHOSPHATE OF A KIDNEY TRANSPORT ADENOSINE TRIPHOSPHATASE BY PHOSPHORYLATION OF A SERINE RESIDUE.

Authors:  L E HOKIN; A YODA
Journal:  Proc Natl Acad Sci U S A       Date:  1964-08       Impact factor: 11.205

Review 2.  ENZYMATIC BASIS FOR ACTIVE TRANSPORT OF NA+ AND K+ ACROSS CELL MEMBRANE.

Authors:  J C SKOU
Journal:  Physiol Rev       Date:  1965-07       Impact factor: 37.312

3.  Sodium-stimulated adenosinetriphosphatase in microsomes from rat brain.

Authors:  J JARNEFELT
Journal:  Biochim Biophys Acta       Date:  1961-03-18

4.  The influence of some cations on an adenosine triphosphatase from peripheral nerves.

Authors:  J C SKOU
Journal:  Biochim Biophys Acta       Date:  1957-02

5.  Experimental demyelination with organo-phosphorus compounds.

Authors:  J M BARNES; F A DENZ
Journal:  J Pathol Bacteriol       Date:  1953-04

6.  Effects of soman and DFP in vivo and in vitro on cerebral metabolism in the rat.

Authors:  R Jović; H S Bachelard; A G Clark; P C Nicholas
Journal:  Biochem Pharmacol       Date:  1971-03       Impact factor: 5.858

7.  On the inhibition of (Na plus, plus, K plus)-activated adenosine triphosphatase by diisopropyl fluorophosphate.

Authors:  A K Lahiri; I B Wilson
Journal:  Mol Pharmacol       Date:  1971-01       Impact factor: 4.436

8.  The effects of varying the cellular and extracellular concentrations of sodium and potassium ions on the uptake of glycine by mouse ascites-tumour cells in the presence and absence of sodium cyanide.

Authors:  A A Eddy
Journal:  Biochem J       Date:  1968-07       Impact factor: 3.857

9.  Effects of some cholinesterase inhibitors on the squid giant axon. Their permeability, detoxication and effects on conduction and acetylcholinesterase activity.

Authors:  F C Hoskin; L T Kremzner; P Rosenberg
Journal:  Biochem Pharmacol       Date:  1969-07       Impact factor: 5.858

10.  Tissue cholinesterase inhibition by 2-carbomethoxy-1-methylvinyl dimethyl phosphate (mevinphos).

Authors:  R P Sharma; J L Shupe; J R Potter
Journal:  Toxicol Appl Pharmacol       Date:  1973-04       Impact factor: 4.219
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  3 in total

1.  Target enzyme inhibition by novel thion analogues of monocrotophos: an acute in vivo study in the rat.

Authors:  M K Siddiqui; M F Rahman; M Mustafa
Journal:  Bull Environ Contam Toxicol       Date:  1993-09       Impact factor: 2.151

2.  Differential expression profile of membrane proteins in Aplysia pleural–pedal ganglia under the stress of methyl parathion.

Authors:  Ying-Ying Chen; Lin Huang; Yong Zhang; Cai-Huan Ke; He-Qing Huang
Journal:  Environ Sci Pollut Res Int       Date:  2014-03       Impact factor: 4.223

3.  The carbamate insecticide ZZ-Aphox induced structural changes of gills, liver, gall-bladder, heart, and notochord of Rana perezi tadpoles.

Authors:  M Pilar Honrubia; M Paz Herráez; R Alvarez
Journal:  Arch Environ Contam Toxicol       Date:  1993-08       Impact factor: 2.804
  3 in total

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