Literature DB >> 13931449

Thalidomide: effect upon pregnancy in the rhesus monkey.

J F LUCEY, R E BEHRMAN.   

Abstract

Thalidomide was administered to 44 female rhesus monkeys immediately after they had mated. There were no live births from these animals, whereas there were 11 live births in 57 untreated monkeys. The results are statistically significant. The hypothesis is advanced that thalidomide killed the embryo prior to implantation.

Entities:  

Keywords:  PREGNANCY, ANIMAL; THALIDOMIDE

Mesh：

Substances：

Year:  1963        PMID： 13931449     DOI： 10.1126/science.139.3561.1295

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  3 in total

1.  THALIDOMIDE INDUCED ALTERATIONS IN THE BLASTOCYST AND PLACENTA OF THE ARMADILLO, DASYPUS NOVEMCINCTUS MEXICANUS, INCLUDING A CHORIOCARCINOMA.

Authors:  M MARIN-PADILLA; K BENIRSCHKE
Journal:  Am J Pathol       Date:  1963-12       Impact factor: 4.307

2.  [Clinical aspects on chemically produced malformations in animals].

Authors:  L Schreiner; T von Kreybig
Journal:  Arch Klin Exp Ohren Nasen Kehlkopfheilkd       Date:  1968-05-09

3.  Crbn I391V is sufficient to confer in vivo sensitivity to thalidomide and its derivatives in mice.

Authors:  Emma C Fink; Marie McConkey; Dylan N Adams; Saurav D Haldar; James A Kennedy; Andrew A Guirguis; Namrata D Udeshi; D R Mani; Michelle Chen; Brian Liddicoat; Tanya Svinkina; Andrew T Nguyen; Steven A Carr; Benjamin L Ebert
Journal:  Blood       Date:  2018-07-31       Impact factor: 25.476
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.