Literature DB >> 13924604

Interference with deiodination of some thyroxine analogues in the rat.

L VAN MIDDLESWORTH, S L JONES.   

Abstract

Entities:  

Keywords:  GOITER/prevention and control; IODINE/metabolism; THIOURACIL/pharmacology; THYROXIN/metabolism; TRIIODOTHYRONINE/metabolism

Mesh：

Substances：

Year:  1961        PMID： 13924604     DOI： 10.1210/endo-69-6-1085

Source DB:  PubMed          Journal:  Endocrinology        ISSN： 0013-7227            Impact factor:   4.736


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  3 in total

1.  Propylthiouracil blocks extrathyroidal conversion of thyroxine to triiodothyronine and augments thyrotropin secretion in man.

Authors:  D L Geffner; M Azukizawa; J M Hershman
Journal:  J Clin Invest       Date:  1975-02       Impact factor: 14.808

2.  Degradation of thyroid hormones by phagocytosing human leukocytes.

Authors:  S J Klebanoff; W L Green
Journal:  J Clin Invest       Date:  1973-01       Impact factor: 14.808

3.  Propylthiouracil inhibits the conversion of L-thyroxine to L-triiodothyronine. An explanation of the antithyroxine effect of propylthiouracil and evidence supporting the concept that triiodothyronine is the active thyroid hormone.

Authors:  J H Oppenheimer; H L Schwartz; M I Surks
Journal:  J Clin Invest       Date:  1972-09       Impact factor: 14.808
  3 in total

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