Occurrence of Clostridium difficile in infections of man.

Smith, Louis DS. (Montana State College, Bozeman) and Elizabeth O. King. Occurrence of Clostridium difficile in infections of man. J. Bacteriol. 84:65-67. 1962-Eight strains of Clostridium difficile were isolated from cases of infection in man in seven different bacteriological laboratories. One of these was isolated from a case of gas gangrene, one from an abscess following a fractured femur, one from a blood culture from an infant, two from pleural fluid, two from peritoneal fluid, and one from an abscess in the vaginal vault. There was no evidence, in these cases, that C. difficile is pathogenic for man. All strains were typical morphologically and culturally and were lethal when inoculated intramuscularly into guinea pigs.