Literature DB >> 1390895

cDNA sequence for rat dermatan sulfate proteoglycan-II (decorin).

S R Abramson1, J F Woessner.   

Abstract

A cDNA clone for dermatan sulfate proteoglycan-II, or decorin, has been isolated from a rat uterus library and sequenced. The cDNA and deduced amino acid sequences are 79 and 77% identical to the previously reported human and bovine sequences, respectively. The rat protein contains potential attachment sites for two glycosaminoglycan chains and four N-linked oligosaccharides, six conserved cysteine residues and multiple repeats of a leucine-rich sequence, LXXLXLXXNXL/I. Overlapping the C-end of one of these repeats is an NKISK sequence, which has been implicated in binding to fibronectin.

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Year:  1992        PMID: 1390895     DOI: 10.1016/0167-4781(92)90019-v

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN: 0006-3002


  2 in total

1.  Effects of transforming growth factor-beta1 on the gene expression of decorin, biglycan, and alkaline phosphatase in osteoblast precursor cells and more differentiated osteoblast cells.

Authors:  T Yamada; N Kamiya; D Harada; M Takagi
Journal:  Histochem J       Date:  1999-10

2.  Presence of pro-forms of decorin and biglycan in human articular cartilage.

Authors:  P J Roughley; R J White; J S Mort
Journal:  Biochem J       Date:  1996-09-15       Impact factor: 3.857

  2 in total

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