| Literature DB >> 13907478 |
Abstract
Two cases of pigmentation of the skeletal system due to tetracycline are reported. It is suggested that tetracycline may be stored in bone due to a tetracycline hydrochloride calcium phosphate complex after prolonged tetracycline administration, and that tetracycline may be the antibiotic of choice in certain cases of osteomyelitis. Dark pigmentation of the teeth may be due to prolonged tetracycline therapy and may be the only sign of heavy deposition into the skeletal system.Entities:
Keywords: BONE AND BONES/metabolism; PIGMENTATION DISORDERS/etiology; TETRACYCLINE/metabolism
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Year: 1962 PMID: 13907478 PMCID: PMC480356 DOI: 10.1136/jcp.15.2.112
Source DB: PubMed Journal: J Clin Pathol ISSN: 0021-9746 Impact factor: 3.411