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Literature DB >> 1390272

Biological monitoring of workers exposed to acetone in acetate fibre plants.

A Fujino¹, T Satoh, T Takebayashi, H Nakashima, H Sakurai, T Higashi, H Matumura, H Minaguchi, T Kawai.

Abstract

Concentrations of acetone in urine, alveolar air, and blood were measured by gas chromatography with flame ionisation detection for 110 subjects occupationally exposed to acetone (mean 372 ppm) in three factories. Significant relations were found between the time weighted average environmental concentration and the concentration in the biological samples. The strongest correlation was between the concentration of acetone in urine and the degree of exposure (r = 0.71, 95% CI 0.64-0.77). This suggests that urinary acetone concentration is the best biological index of occupational exposure to acetone.

Entities: Chemical

Mesh：

Substances：
Acetone

Year: 1992 PMID： 1390272 PMCID： PMC1039311 DOI： 10.1136/oem.49.9.654

Source DB: PubMed Journal: Br J Ind Med ISSN： 0007-1072

17 in total

Biological monitoring of workers exposed to acetone in acetate fibre plants.

Review 1. Uptake of solvents in the blood and tissues of man. A review.

2. Body burden profiles of single and mixed solvent exposures.

3. Exposure of man and dog to low concentrations of acetone vapor.

4. Uptake of solvents from the lungs.

5. Biomonitoring of industrial solvent exposures in workers' alveolar air.

6. Biological monitoring of persons exposed to methanol vapours.

7. [Neonatal mortality among boys and girls in Denmark, born 1980-1987].

8. Urinary excretion of unmetabolized acetone as an indicator of occupational exposure to acetone.

9. n-Hexane urine elimination and weighted exposure concentration.

10. Partition coefficients of some aromatic hydrocarbons and ketones in water, blood and oil.

Review 1. Gases and organic solvents in urine as biomarkers of occupational exposure: a review.

2. Physiologically based pharmacokinetic model for acetone.

3. Relationship between acetone exposure concentration and health effects in acetate fiber plant workers.

4. Blood acetone concentration in "normal people" and in exposed workers 16 h after the end of the workshift.

5. Acetone excretion into urine of workers exposed to acetone in acetate fiber plants.