Literature DB >> 1389733

Early and long term results of re-operation for coronary artery disease.

E S Akl1, E Ozdogan, S K Ohri, M Barbir, J A Gaer, A G Mitchell, M H Yacoub.   

Abstract

OBJECTIVE: To define the incidence, possible causes, operative procedure, and early and medium term results of patients undergoing reoperation for coronary artery disease.
DESIGN: A retrospective analysis of patients undergoing reoperation in one hospital during a 10 year period.
SETTING: A regional cardiothoracic centre. PATIENTS: 115 patients had reoperation for recurrent angina, 1-17 years (mean (SD) 7.4 (3.9)) after primary revascularisation. MAIN OUTCOME MEASURES: They received 279 grafts (2.4 grafts per patient); 58% of the grafts were anasatomosed to previously grafted vessels. The internal mammary artery was used in 87% of patients who required grafts to the left anterior descending coronary artery.
RESULTS: Reoperation accounted for 8.3% of the total number of patients who underwent coronary bypass grafting. Graft failure alone or in combination with other factors was judged to be the cause of recurrence of symptoms in 87%. 42% of patients had two or more coronary risk factors. The early mortality was 5.2% and the actuarial survival at five and 10 years was 90.4% and 88.4% respectively. 85% of the survivors had initial complete relief of angina and 14% had partial improvement. Freedom from recurrent symptoms at five and 10 years was 66.6% and 34.6% respectively.
CONCLUSIONS: Vein graft failure either alone or in combination with progression of native coronary disease is the main cause for symptomatic deterioration after bypass grafting. Reoperation can be performed with slightly increased risk and can give good early and medium term results.

Entities:  

Mesh:

Year:  1992        PMID: 1389733      PMCID: PMC1025009          DOI: 10.1136/hrt.68.8.176

Source DB:  PubMed          Journal:  Br Heart J        ISSN: 0007-0769


  23 in total

1.  Incidence, risk, and outcome of reintervention after aortocoronary bypass surgery.

Authors:  K Laird-Meeter; R van Domburg; M J van den Brand; J Lubsen; E Bos; P G Hugenholtz
Journal:  Br Heart J       Date:  1987-05

2.  Improvement in early saphenous vein graft patency after coronary artery bypass surgery with antiplatelet therapy: results of a Veterans Administration Cooperative Study.

Authors:  S Goldman; J Copeland; T Moritz; W Henderson; K Zadina; T Ovitt; J Doherty; R Read; E Chesler; Y Sako
Journal:  Circulation       Date:  1988-06       Impact factor: 29.690

3.  Occlusive changes at the coronary artery--bypass graft anastomosis. Morphologic study of 95 grafts.

Authors:  L S Griffith; B H Bulkley; G M Hutchins; R K Brawley
Journal:  J Thorac Cardiovasc Surg       Date:  1977-05       Impact factor: 5.209

4.  Lipoproteins and the pathogenesis of atherosclerosis.

Authors:  D Steinberg
Journal:  Circulation       Date:  1987-09       Impact factor: 29.690

5.  Regulation of low-density lipoprotein receptors: implications for pathogenesis and therapy of hypercholesterolemia and atherosclerosis.

Authors:  J L Goldstein; M S Brown
Journal:  Circulation       Date:  1987-09       Impact factor: 29.690

6.  Results of reoperation for recurrent angina pectoris.

Authors:  W I Norwood; L H Cohn; J J Collins
Journal:  Ann Thorac Surg       Date:  1977-01       Impact factor: 4.330

7.  Accelerated "atherosclerosis". A morphologic study of 97 saphenous vein coronary artery bypass grafts.

Authors:  B H Bulkley; G M Hutchins
Journal:  Circulation       Date:  1977-01       Impact factor: 29.690

8.  Beneficial effects of combined colestipol-niacin therapy on coronary atherosclerosis and coronary venous bypass grafts.

Authors:  D H Blankenhorn; S A Nessim; R L Johnson; M E Sanmarco; S P Azen; L Cashin-Hemphill
Journal:  JAMA       Date:  1987-06-19       Impact factor: 56.272

9.  Fifteen hundred coronary reoperations. Results and determinants of early and late survival.

Authors:  B W Lytle; F D Loop; D M Cosgrove; P C Taylor; M Goormastic; W Peper; C C Gill; L A Golding; R W Stewart
Journal:  J Thorac Cardiovasc Surg       Date:  1987-06       Impact factor: 5.209

10.  Endothelium-derived relaxing factor and protection against contractions induced by histamine and serotonin in the human internal mammary artery and in the saphenous vein.

Authors:  Z H Yang; D Diederich; K Schneider; R Siebenmann; P Stulz; L von Segesser; M Turina; F R Bühler; T F Lüscher
Journal:  Circulation       Date:  1989-10       Impact factor: 29.690

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