Literature DB >> 13891472

The uricosuria and orotic aciduria induced by 6-azauridine.

H J FALLON, E FREI, J BLOCK, J E SEEGMILLER.   

Abstract

Entities:  

Keywords:  ANTINEOPLASTIC AGENTS/pharmacology; OROTIC ACID/urine; URIC ACID/urine

Mesh：

Substances：

Year:  1961        PMID： 13891472      PMCID： PMC290889          DOI： 10.1172/JCI104415

Source DB:  PubMed          Journal:  J Clin Invest        ISSN： 0021-9738            Impact factor:   14.808


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  28 in total

1.  Orotidylic acid decarboxylase: inhibition studies with azauridine 5'-phosphate.

Authors:  R E HANDSCHUMACHER
Journal:  J Biol Chem       Date:  1960-10       Impact factor: 5.157

2.  Dangers of uric-acid excretion during treatment of leukaemia and lymphosarcoma.

Authors:  D GREENBAUM; H F H STONE
Journal:  Lancet       Date:  1959-01-10       Impact factor: 79.321

3.  Refractory megaloblastic anemia associated with excretion of orotic acid.

Authors:  C M HUGULEY; J A BAIN; S L RIVERS; R B SCOGGINS
Journal:  Blood       Date:  1959-06       Impact factor: 22.113

4.  Gout and blood dyscrasias.

Authors:  J H TALBOTT
Journal:  Medicine (Baltimore)       Date:  1959-05       Impact factor: 1.889

5.  The enzymatic spectrophotometric method for determination of uric acid.

Authors:  L LIDDLE; J E SEEGMILLER; L LASTER
Journal:  J Lab Clin Med       Date:  1959-12

6.  Control by uracil of formation of enzymes required for orotate synthesis.

Authors:  R A YATES; A B PARDEE
Journal:  J Biol Chem       Date:  1957-08       Impact factor: 5.157

7.  Renal regulation of uric acid excretion in normal and gouty man; modification by uricosuric agents.

Authors:  A B GUTMAN; T F YU
Journal:  Bull N Y Acad Med       Date:  1958-05

8.  Control of pyrimidine biosynthesis in Escherichia coli by a feed-back mechanism.

Authors:  A B PARDEE; R A YATES
Journal:  J Biol Chem       Date:  1956-08       Impact factor: 5.157

9.  The effect of phenylbutazone on uric acid metabolism in two normal subjects.

Authors:  J B WYNGAARDEN
Journal:  J Clin Invest       Date:  1955-02       Impact factor: 14.808

10.  Orotic acid in milk.

Authors:  L E HALLANGER; J W LAAKSO; M O SCHULTZE
Journal:  J Biol Chem       Date:  1953-05       Impact factor: 5.157
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  11 in total

1.  THE EFFECT OF 6-AZAURIDINE ADMINISTRATION ON DE NOVO PYRIMIDINE PRODUCTION IN CHRONIC MYELOGENOUS LEUKEMIA.

Authors:  V H BONO; S M WEISSMAN; E FREI
Journal:  J Clin Invest       Date:  1964-07       Impact factor: 14.808

2.  HYPOCHOLESTEROLAEMIA AND OROTIC ACIDURIA DURING TREATMENT WITH 6-AZAURIDINE.

Authors:  A S BUTTOO; M C ISRAUELS; J F WILKINSON
Journal:  Br Med J       Date:  1965-02-27

3.  The metabolism of ring-labeled orotic acid in man.

Authors:  S M WEISSMAN; A Z EISEN; H FALLON; M LEWIS; M KARON
Journal:  J Clin Invest       Date:  1962-07       Impact factor: 14.808

Review 4.  New indications for 6-azauridine treatment in man. A review.

Authors:  J Elis; H Rasková
Journal:  Eur J Clin Pharmacol       Date:  1972-03       Impact factor: 2.953

5.  The determination of orotic acid in the blood serum by means of the spectrophotometric method.

Authors:  A Stajner; J Sůva; F Musil
Journal:  Experientia       Date:  1968-02-15

6.  Mechanism of overproduction of orotic acid by a mutant of Brevibacterium ammoniagenes.

Authors:  H Skodová; J Skoda
Journal:  Appl Microbiol       Date:  1969-01

Review 7.  Pharmacology of uricosuric drugs.

Authors:  I Kippen; M W Whitehouse; J R Klinenberg
Journal:  Ann Rheum Dis       Date:  1974-07       Impact factor: 19.103

8.  Reabsorption of monocarboxylic acids in the proximal tubule of the rat kidney. III. Specificity for aromatic compounds.

Authors:  K J Ullrich; G Rumrich; S Klöss; H Fasold
Journal:  Pflugers Arch       Date:  1982-11-11       Impact factor: 3.657

9.  Physiologic Medium Rewires Cellular Metabolism and Reveals Uric Acid as an Endogenous Inhibitor of UMP Synthase.

Authors:  Jason R Cantor; Monther Abu-Remaileh; Naama Kanarek; Elizaveta Freinkman; Xin Gao; Abner Louissaint; Caroline A Lewis; David M Sabatini
Journal:  Cell       Date:  2017-04-06       Impact factor: 41.582

10.  A study of dose-response relationships of allopurinol in the presence of low or high purine turnover.

Authors:  W Löffler; W Gröbner
Journal:  Klin Wochenschr       Date:  1988-02-15
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