Literature DB >> 1388775

Synthesis and antihypertensive activity of imidazo[2,1-b]-thiazoles bearing a 2,6-dichlorophenyl group.

A Andreani1, M Rambaldi, A Locatelli, A Cristoni, S Malandrino, G Pifferi.   

Abstract

A number of imidazo[2,1-b]thiazoles bearing a 2,6-dichlorophenyl group as hydrazone or as amide were prepared and tested in rats as antihypertensive agents. Only compounds bearing a chlorine at position 6 were active.

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Year:  1992        PMID: 1388775

Source DB:  PubMed          Journal:  Acta Pharm Nord        ISSN: 1100-1801


  3 in total

1.  Rational synthesis, anticancer activity, and molecular docking studies of novel benzofuran liked thiazole hybrids.

Authors:  Sanjay D Hadiyal; Jaydeep N Lalpara; Bhavin B Dhaduk; H S Joshi
Journal:  Mol Divers       Date:  2022-07-19       Impact factor: 3.364

2.  Design, synthesis and biological evaluation of benzo-[d]-imidazo-[2,1-b]-thiazole and imidazo-[2,1-b]-thiazole carboxamide triazole derivatives as antimycobacterial agents.

Authors:  Surendar Chitti; Kevin Van Calster; Davie Cappoen; Adinarayana Nandikolla; Yogesh Mahadu Khetmalis; Paul Cos; Banoth Karan Kumar; Sankaranarayanan Murugesan; Kondapalli Venkata Gowri Chandra Sekhar
Journal:  RSC Adv       Date:  2022-08-10       Impact factor: 4.036

3.  Design and synthesis of novel Imidazo[2,1-b]thiazole derivatives as potent antiviral and antimycobacterial agents.

Authors:  Elif Gürsoy; Efe Doğukan Dincel; Lieve Naesens; Nuray Ulusoy Güzeldemirci
Journal:  Bioorg Chem       Date:  2019-12-06       Impact factor: 5.275

  3 in total

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