| Literature DB >> 13886836 |
M C DODD, N J BIGLEY, V B GEYER, F W McCOY, H E WILSON.
Abstract
Autoimmune hemolytic anemia and leukopenia, circulating autoantibodies for erythrocytes, leukocytes, and ribosomes; pathological changes in liver, spleen, heart, brain, and kidneys were produced in rabbits injected with rat or rabbit liver ribosomes. The hematologic and pathologic changes were reproduced by injection of anti-ribosomal serum into normal rabbits. The autoantibody specificity was related primarily to nucleotides and nucleosides.Entities:
Keywords: IMMUNITY; LIVER/chemistry; NUCLEOPROTEINS/pharmacology
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Year: 1962 PMID： 13886836 DOI： 10.1126/science.137.3531.688
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728