Literature DB >> 1388050

The Wnt gene family in tumorigenesis and in normal development.

R Nusse1.   

Abstract

Various members of the Wnt gene family have been identified as activated oncogenes in mouse mammary tumors. We show that some tumors are oligoclonal for activation of a Wnt gene, and clonal variation when those tumors are transplanted to become hormone-independent. The normal function of many Wnt genes is to control pattern formation in early embryos, as shown by expression profiles and by mutant analysis.

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Year:  1992        PMID： 1388050     DOI： 10.1016/0960-0760(92)90181-h

Source DB:  PubMed          Journal:  J Steroid Biochem Mol Biol        ISSN： 0960-0760            Impact factor:   4.292


  16 in total

1.  Eye formation in the absence of retina.

Authors:  Eric C Swindell; Chaomei Liu; Rina Shah; April N Smith; Richard A Lang; Milan Jamrich
Journal:  Dev Biol       Date:  2008-07-16       Impact factor: 3.582

2.  Glucocorticoid excess in mice results in early activation of osteoclastogenesis and adipogenesis and prolonged suppression of osteogenesis: a longitudinal study of gene expression in bone tissue from glucocorticoid-treated mice.

Authors:  Wei Yao; Zhiqiang Cheng; Cheryl Busse; Aaron Pham; Mary C Nakamura; Nancy E Lane
Journal:  Arthritis Rheum       Date:  2008-06

Review 3.  Regulation of CLU gene expression by oncogenes and epigenetic factors implications for tumorigenesis.

Authors:  Arturo Sala; Saverio Bettuzzi; Sabina Pucci; Olesya Chayka; Michael Dews; Andrei Thomas-Tikhonenko
Journal:  Adv Cancer Res       Date:  2009       Impact factor: 6.242

4.  Adherens junction proteins in the hamster uterus: their contributions to the success of implantation.

Authors:  Liming Luan; Tianbing Ding; Amanda Stinnett; Jeff Reese; Bibhash C Paria
Journal:  Biol Reprod       Date:  2011-07-13       Impact factor: 4.285

5.  Gene expression profiling of mice with genetically modified muscle glycogen content.

Authors:  Gretchen E Parker; Bartholomew A Pederson; Mariko Obayashi; Jill M Schroeder; Robert A Harris; Peter J Roach
Journal:  Biochem J       Date:  2006-04-01       Impact factor: 3.857

Review 6.  Osteosarcoma development and stem cell differentiation.

Authors:  Ni Tang; Wen-Xin Song; Jinyong Luo; Rex C Haydon; Tong-Chuan He
Journal:  Clin Orthop Relat Res       Date:  2008-06-18       Impact factor: 4.176

7.  Glucocorticoid-induced bone loss in mice can be reversed by the actions of parathyroid hormone and risedronate on different pathways for bone formation and mineralization.

Authors:  Wei Yao; Zhiqiang Cheng; Aaron Pham; Cheryl Busse; Elizabeth A Zimmermann; Robert O Ritchie; Nancy E Lane
Journal:  Arthritis Rheum       Date:  2008-11

8.  Secreted frizzled-related protein 4 is a potent tumor-derived phosphaturic agent.

Authors:  Theresa Berndt; Theodore A Craig; Ann E Bowe; John Vassiliadis; David Reczek; Richard Finnegan; Suzanne M Jan De Beur; Susan C Schiavi; Rajiv Kumar
Journal:  J Clin Invest       Date:  2003-09       Impact factor: 14.808

Review 9.  Pre-clinical applications of transgenic mouse mammary cancer models.

Authors:  C J Kavanaugh; K V Desai; A Calvo; P H Brown; C Couldrey; R Lubet; J E Green
Journal:  Transgenic Res       Date:  2002-12       Impact factor: 2.788

10.  Binding of sFRP-3 to EGF in the extra-cellular space affects proliferation, differentiation and morphogenetic events regulated by the two molecules.

Authors:  Raffaella Scardigli; Cesare Gargioli; Daniela Tosoni; Ugo Borello; Maurilio Sampaolesi; Clara Sciorati; Stefano Cannata; Emilio Clementi; Silvia Brunelli; Giulio Cossu
Journal:  PLoS One       Date:  2008-06-18       Impact factor: 3.240
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