Literature DB >> 13880253

Glucose-6-phosphate dehydrogenase and detoxification of hydrogen peroxide in human erythrocytes.

G COHEN, P HOCHSTEIN.   

Abstract

Human erythrocytes with deficient glucose-6-phosphate dehydrogenase levels are unable to maintain their levels of reduced glutathione in the presence of low-level, steady-state concentrations of hydrogen peroxide. This finding has bearing on the biochemical mechanisms of drug-induced hemolytic anemia.

Entities:  

Keywords:  DEHYDROGENASES/blood; ERYTHROCYTES; HYDROGEN PEROXIDE/blood

Mesh：

Substances：

Year:  1961        PMID： 13880253     DOI： 10.1126/science.134.3492.1756

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  11 in total

1.  OXIDATIVE HEMOLYSIS AND ERYTHROCYTE METABOLISM IN HEREDITARY ACATALASIA.

Authors:  H S JACOB; S H INGBAR; J H JANDL
Journal:  J Clin Invest       Date:  1965-07       Impact factor: 14.808

2.  Studies on drug-induced hemolysis: effects of menadione and its water soluble preparations on the glutathione peroxidase of human erythrocytes.

Authors:  M Vetrella; W Barthelmai
Journal:  Klin Wochenschr       Date:  1972-03-01

3.  [Development of drug induced anemia in patients with glutathione reductase deficiency].

Authors:  H D Waller; H C Benöhr; P Waumans
Journal:  Klin Wochenschr       Date:  1969-01-01

4.  [Hereditary non-spherocytic hemolytic anemia caused by glucose-6-phosphate dehydrogenase deficiency. Formation of an enzyme protein with modified characteristics in the blood cells of a German family].

Authors:  H D Waller; G W Löhr; J Gayer
Journal:  Klin Wochenschr       Date:  1966-02-01

5.  Mechanisms of methylene blue stimulation of the hexose monophosphate shunt in erythrocytes.

Authors:  E N Metz; P Balcerzak; A L Sagone
Journal:  J Clin Invest       Date:  1976-10       Impact factor: 14.808

6.  Peroxidative hemolysis of red blood cells from patients with abetalipoproteinemia (acanthocytosis).

Authors:  J T Dodge; G Cohen; H J Kayden; G B Phillips
Journal:  J Clin Invest       Date:  1967-03       Impact factor: 14.808

7.  Useful agents for the study of glutathione metabolism in erythroyctes. Organic hydroperoxides.

Authors:  S K Srivastava; Y C Awasthi; E Beutler
Journal:  Biochem J       Date:  1974-05       Impact factor: 3.857

8.  Catalase: a tetrameric enzyme with four tightly bound molecules of NADPH.

Authors:  H N Kirkman; G F Gaetani
Journal:  Proc Natl Acad Sci U S A       Date:  1984-07       Impact factor: 11.205

9.  Experimental pulmonary inflammatory injury in the monkey.

Authors:  S D Revak; C L Rice; I U Schraufstätter; W A Halsey; B P Bohl; R M Clancy; C G Cochrane
Journal:  J Clin Invest       Date:  1985-09       Impact factor: 14.808

10.  [Heinz body formation and GSH content in erythrocytes with glucose-6-phosphate dehydrogenase deficiency and disruption of glutathione synthesis after x-irradiation in vitro].

Authors:  H D Waller; H D Schoen
Journal:  Klin Wochenschr       Date:  1966-02-15
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