Literature DB >> 1387094

Lp(a): a link between thrombosis and atherosclerosis.

A M Scanu1.   

Abstract

Lipoprotein(a), or Lp(a), is a lipoprotein having lipid composition similar to that of LDL, but a protein moiety consisting of ApoB 100 linked by disulfide bridge to apo(a), a glycoprotein with structural similarity to plasminogen. Lp(a) can be both atherogenic and thrombogenic. These two actions are likely to be mutually operative, a fact that on a molar basis makes Lp(a) more of a cardiovascular pathogen than LDL.

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Year:  1992        PMID： 1387094     DOI： 10.1007/bf00145354

Source DB:  PubMed          Journal:  Eur J Epidemiol        ISSN： 0393-2990            Impact factor:   8.082


  10 in total

Review 1.  Lipoprotein (a). Heterogeneity and biological relevance.

Authors:  A M Scanu; G M Fless
Journal:  J Clin Invest       Date:  1990-06       Impact factor: 14.808

2.  Lipoprotein(a). A unique risk factor for atherothrombotic disease.

Authors:  J Loscalzo
Journal:  Arteriosclerosis       Date:  1990 Sep-Oct

3.  Quantitation and localization of apolipoproteins [a] and B in coronary artery bypass vein grafts resected at re-operation.

Authors:  G L Cushing; J W Gaubatz; M L Nava; B J Burdick; T M Bocan; J R Guyton; D Weilbaecher; M E DeBakey; G M Lawrie; J D Morrisett
Journal:  Arteriosclerosis       Date:  1989 Sep-Oct

4.  cDNA sequence of human apolipoprotein(a) is homologous to plasminogen.

Authors:  J W McLean; J E Tomlinson; W J Kuang; D L Eaton; E Y Chen; G M Fless; A M Scanu; R M Lawn
Journal:  Nature       Date:  1987 Nov 12-18       Impact factor: 49.962

Review 5.  The mysteries of lipoprotein(a).

Authors:  G Utermann
Journal:  Science       Date:  1989-11-17       Impact factor: 47.728

6.  Solubility, immunochemical, and lipoprotein binding properties of apoB-100-apo[a], the protein moiety of lipoprotein[a].

Authors:  G M Fless; D J Pfaffinger; J D Eisenbart; A M Scanu
Journal:  J Lipid Res       Date:  1990-05       Impact factor: 5.922

Review 7.  Lipoprotein(a): a genetically determined cardiovascular pathogen in search of a function.

Authors:  A M Scanu
Journal:  J Lab Clin Med       Date:  1990-08

8.  Rhesus monkey apolipoprotein(a). Sequence, evolution, and sites of synthesis.

Authors:  J E Tomlinson; J W McLean; R M Lawn
Journal:  J Biol Chem       Date:  1989-04-05       Impact factor: 5.157

9.  Fat feeding in humans induces lipoproteins of density less than 1.006 that are enriched in apolipoprotein [a] and that cause lipid accumulation in macrophages.

Authors:  T P Bersot; T L Innerarity; R E Pitas; S C Rall; K H Weisgraber; R W Mahley
Journal:  J Clin Invest       Date:  1986-02       Impact factor: 14.808

10.  Detection and quantification of lipoprotein(a) in the arterial wall of 107 coronary bypass patients.

Authors:  M Rath; A Niendorf; T Reblin; M Dietel; H J Krebber; U Beisiegel
Journal:  Arteriosclerosis       Date:  1989 Sep-Oct
  10 in total

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