| Literature DB >> 1387066 |
T Motokura1, H F Yi, H M Kronenberg, O W McBride, A Arnold.
Abstract
The PRAD1/cyclin D1 gene (CCND1), a member of the D-type cyclin gene family, has been implicated as a protooncogene in parathyroid, lymphoid, and mammary tumors. We cloned and mapped another member of this family, the human cyclin D3 gene (CCND3), to chromosome 6p----q13 using human x rodent hybrids. This assignment raises the hypothesis that cyclin D3 may be involved in the pathogenesis of human neoplasms with abnormalities of chromosome 6.Entities:
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Year: 1992 PMID： 1387066 DOI： 10.1159/000133359
Source DB: PubMed Journal: Cytogenet Cell Genet ISSN： 0301-0171