Literature DB >> 1386848

Serotonergic medications for sexual obsessions, sexual addictions, and paraphilias.

D J Stein1, E Hollander, D T Anthony, F R Schneier, B A Fallon, M R Liebowitz, D F Klein.   

Abstract

BACKGROUND: Paraphilias and related disorders have recently been thought of as sexual addictions. However, it has also been argued that these disorders are sexual compulsions. The question arises as to whether these disorders and obsessive compulsive disorder respond in the same way to pharmacotherapy.
METHOD: We retrospectively reviewed outcome in 13 patients who presented with sexual symptoms and were treated with serotonin reuptake blockers. Symptoms were divided into paraphilias, nonparaphilic sexual addictions, and sexual obsessions.
RESULTS: Paraphilias had the least improvement, while sexual obsessions had the best response to medication.
CONCLUSION: Paraphilias and related disorders may be less responsive than sexual obsessions or compulsions to serotonin reuptake blockers. Perhaps paraphilias and related disorders are on the impulsive rather than the compulsive end of the spectrum of obsessive compulsive disorders. Controlled trials are, however, necessary to replicate these preliminary findings.

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Year:  1992        PMID: 1386848

Source DB:  PubMed          Journal:  J Clin Psychiatry        ISSN: 0160-6689            Impact factor:   4.384


  11 in total

Review 1.  The paraphilias, obsessive compulsive spectrum disorder, and the treatment of sexually deviant behaviour.

Authors:  J M Bradford
Journal:  Psychiatr Q       Date:  1999

2.  A case of late-onset pedophilia and response to sertraline.

Authors:  Naren Prahlada Rao; Prabhat K Chand; Pratima Murthy
Journal:  Prim Care Companion J Clin Psychiatry       Date:  2007

3.  Potential implications of research on genetic or heritable contributions to pedophilia for the objectives of criminal law.

Authors:  Colleen M Berryessa
Journal:  Recent Adv DNA Gene Seq       Date:  2014

4.  Treatment of compulsive sexual behaviour with clomipramine and valproic acid.

Authors:  Murat Gulsun; Zeynep Gulcat; Hamdullah Aydin
Journal:  Clin Drug Investig       Date:  2007       Impact factor: 2.859

Review 5.  Current concepts in the pharmacotherapy of paraphilias.

Authors:  Frederico D Garcia; Florence Thibaut
Journal:  Drugs       Date:  2011-04-16       Impact factor: 9.546

6.  Obsessive-compulsive spectrum disorders.

Authors:  Andrea Allen; Audrey King; Eric Hollander
Journal:  Dialogues Clin Neurosci       Date:  2003-09       Impact factor: 5.986

Review 7.  Epidemiologic and clinical updates on impulse control disorders: a critical review.

Authors:  Bernardo Dell'Osso; A Carlo Altamura; Andrea Allen; Donatella Marazziti; Eric Hollander
Journal:  Eur Arch Psychiatry Clin Neurosci       Date:  2006-09-07       Impact factor: 5.270

8.  Topiramate plus citalopram in the treatment of Compulsive-Impulsive Sexual Behaviors.

Authors:  Donatella Marazziti; Bernardo Dell'Osso
Journal:  Clin Pract Epidemiol Ment Health       Date:  2006-05-22

9.  Fetishistic transvestism in a patient with mental retardation and psychosis.

Authors:  Rajmohan Velayudhan; Asfia Khaleel; Nideesh Sankar; Manoj Kumar; Firoz Kazhungil; Thazhe Mangool Raghuram
Journal:  Indian J Psychol Med       Date:  2014-04

10.  Treatment of transvestic fetishism with fluoxetine: a case report.

Authors:  Mohammad Amir Usmani; Rakesh K Gaur; Suhail Ahmad Azmi; Sheshank Gangwar
Journal:  Iran J Psychiatry Behav Sci       Date:  2012
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