Literature DB >> 13864331

Analysis of different cell systems for the production of attenuated poliomyelitis virus vaccine.

M BALDUCCI, R SANTORO, G MANCINI, D BALDUCCI.   

Abstract

THE OPTIMAL CELLULAR SYSTEM TO PRODUCE ATTENUATED VIRUS VACCINE SHOULD HAVE THE FOLLOWING CHARACTERISTICS: ease and reproducibility of preparation, ability to produce virus at high titer, absence of latent viruses, and diploid chromosome complement. At the present, primary monkey kidney is still the cellular system of choice but other systems appear to be promising.

Entities:  

Keywords:  VACCINES

Mesh:

Substances:

Year:  1962        PMID: 13864331      PMCID: PMC1057839          DOI: 10.1128/am.10.3.190-192.1962

Source DB:  PubMed          Journal:  Appl Microbiol        ISSN: 0003-6919


  4 in total

1.  The vacuolating virus, S.V. 40.

Authors:  B H SWEET; M R HILLEMAN
Journal:  Proc Soc Exp Biol Med       Date:  1960-11

2.  Propagation of poliovirus, measles, and vaccinia in guinea pig spleen cell strains.

Authors:  C C MASCOLI; L V STANFIELD; L N PHELPS
Journal:  Science       Date:  1959-04-03       Impact factor: 47.728

3.  The serial propagation of poliomyelitis viruses in cells derived from rabbit embryo kidney.

Authors:  F W SHEFFIELD; G M CHURCHER
Journal:  Br J Exp Pathol       Date:  1957-04

4.  Genetics of somatic mammalian cells. II. Chromosomal constitution of cells in tissue culture.

Authors:  J H TJIO; T T PUCK
Journal:  J Exp Med       Date:  1958-08-01       Impact factor: 14.307

  4 in total

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