Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Cell extracts of Candida albicans block adherence of the organisms to endothelial cells.

Literature DB >> 1386347

Cell extracts of Candida albicans block adherence of the organisms to endothelial cells.

J E Edwards¹, C L Mayer, S G Filler, E Wadsworth, R A Calderone.

Abstract

Cell extracts of Candida albicans were fractionated by concanavalin A affinity chromatography. Eluted mannosylated proteins (fraction II) and nonbinding, nonmannosylated proteins (fraction I) were collected and assayed directly for inhibition of adherence of C. albicans to endothelium. Fraction II blocked blastospore adherence to endothelial cells. Fraction I blocked both blastospore and germ tube adherence to endothelial cells. Monoclonal antibody OKM-1 (anti-CR3) and an anti-C. albicans monoclonal antibody, CA-A (anti-CR2), reacted in Western blots with proteins from fraction I, suggesting the presence of the CR2- and CR3-like proteins that have been previously identified on C. albicans germ tubes.

Entities: Species

Mesh：

Substances：

Year: 1992 PMID： 1386347 PMCID： PMC257285 DOI： 10.1128/iai.60.8.3087-3091.1992

Source DB: PubMed Journal: Infect Immun ISSN： 0019-9567 Impact factor: 3.441

26 in total

1. Candida albicans C3d receptor, isolated by using a monoclonal antibody.

Authors: L Linehan; E Wadsworth; R Calderone
Journal: Infect Immun Date: 1988-08 Impact factor: 3.441

2. Tunicamycin--an inhibitor of yeast glycoprotein synthesis.

Authors: S C Kuo; J O Lampen
Journal: Biochem Biophys Res Commun Date: 1974-05-07 Impact factor: 3.575

3. Extracellular polymer of Candida albicans: isolation, analysis and role in adhesion.

Authors: J McCourtie; L J Douglas
Journal: J Gen Microbiol Date: 1985-03

4. Inhibition of adherence of Candida albicans to human epithelial cells.

Authors: R L Sandin; A L Rogers
Journal: Mycopathologia Date: 1982-01-15 Impact factor: 2.574

5. An enzyme-linked immunosorbent assay for quantifying adherence of Candida to human vascular endothelium.

Authors: S G Filler; L C Der; C L Mayer; P D Christenson; J E Edwards
Journal: J Infect Dis Date: 1987-10 Impact factor: 5.226

6. Abnormalities of polymorphonuclear leukocyte function associated with a heritable deficiency of high molecular weight surface glycoproteins (GP138): common relationship to diminished cell adherence.

Authors: D C Anderson; F C Schmalstieg; M A Arnaout; S Kohl; M F Tosi; N Dana; G J Buffone; B J Hughes; B R Brinkley; W D Dickey
Journal: J Clin Invest Date: 1984-08 Impact factor: 14.808

7. An endothelial cell surface factor(s) induced in vitro by lipopolysaccharide, interleukin 1, and tumor necrosis factor-alpha increases neutrophil adherence by a CDw18-dependent mechanism.

Authors: T H Pohlman; K A Stanness; P G Beatty; H D Ochs; J M Harlan
Journal: J Immunol Date: 1986-06-15 Impact factor: 5.422

8. Characterization of Candida albicans adherence to human vaginal epithelial cells in vitro.

Authors: J C Lee; R D King
Journal: Infect Immun Date: 1983-09 Impact factor: 3.441

9. C3bi-binding protein on Candida albicans: temperature-dependent expression and relationship to human complement receptor type 3.

Authors: A Eigentler; T F Schulz; C Larcher; E M Breitwieser; B L Myones; A L Petzer; M P Dierich
Journal: Infect Immun Date: 1989-02 Impact factor: 3.441

10. Expression of specific binding sites on Candida with functional and antigenic characteristics of human complement receptors.

Authors: J E Edwards; T A Gaither; J J O'Shea; D Rotrosen; T J Lawley; S A Wright; M M Frank; I Green
Journal: J Immunol Date: 1986-12-01 Impact factor: 5.422

9 in total

Review 1. Antifungal agents: chemotherapeutic targets and immunologic strategies.

Authors: N H Georgopapadakou; T J Walsh
Journal: Antimicrob Agents Chemother Date: 1996-02 Impact factor: 5.191

Review 2. Cell wall and secreted proteins of Candida albicans: identification, function, and expression.

Authors: W L Chaffin; J L López-Ribot; M Casanova; D Gozalbo; J P Martínez
Journal: Microbiol Mol Biol Rev Date: 1998-03 Impact factor: 11.056

3. Cloning and characterization of CAD1/AAF1, a gene from Candida albicans that induces adherence to endothelial cells after expression in Saccharomyces cerevisiae.

Authors: Y Fu; S G Filler; B J Spellberg; W Fonzi; A S Ibrahim; T Kanbe; M A Ghannoum; J E Edwards
Journal: Infect Immun Date: 1998-05 Impact factor: 3.441

4. Relative abundance of oligosaccharides in Candida species as determined by fluorophore-assisted carbohydrate electrophoresis.

Authors: T L Goins; J E Cutler
Journal: J Clin Microbiol Date: 2000-08 Impact factor: 5.948