Literature DB >> 13854787

Increased incidence of non-tasters of phenylthiocarbamide among congenital athyreotic cretins.

T H SHEPARD, S M GARTLER.   

Abstract

The incidence of nontasters for phenylthiocarbamide was found to be significantly higher in 27 athyreotic cretins than in normal adults and children. A significant increase of nontasters among the parents and siblings of these cretins was also found. These findings are discussed in relation to maldevelopment of the fetal thyroid in nontaster genotypes.

Entities:  

Keywords:  CRETINISM/physiology; TASTE/genetics; THIOUREA/related compounds

Mesh：

Substances：

Year:  1960        PMID： 13854787     DOI： 10.1126/science.131.3404.929

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  9 in total

1.  PTC TASTE SENSITIVITY AND ENDEMIC GOITER IN BRAZIL.

Authors:  E AZEVEDO; H KRIEGER; M P MI; N E MORTON
Journal:  Am J Hum Genet       Date:  1965-01       Impact factor: 11.025

2.  PHENYLTHIOCARBAMIDE NON-TASTING AMONG CONGENITAL ATHYROTIC CRETINS: FURTHER STUDIES IN AN ATTEMPT TO EXPLAIN THE INCREASED INCIDENCE.

Authors:  T H Shepard
Journal:  J Clin Invest       Date:  1961-09       Impact factor: 14.808

3.  Thyroid-binding globulin deficiency in a patient with Beckwith's syndrome.

Authors:  S L Kaufman; R Frederickson
Journal:  Calif Med       Date:  1973-04

4.  New data on the association between PTC and thyroid diseases.

Authors:  H M Mendez de Araújo; F M Salzano; H Wolff
Journal:  Humangenetik       Date:  1972

5.  Congenital hypothyroidism and hyperthyroidism in monozygotic twin girls.

Authors:  P L Townes; W L Bradford
Journal:  J Med Genet       Date:  1971-12       Impact factor: 6.318

6.  Leprosy and genetics. A review of past research with remarks concerning future investigations.

Authors:  B Beiguelman
Journal:  Bull World Health Organ       Date:  1967       Impact factor: 9.408

Review 7.  The genetics of phenylthiocarbamide perception.

Authors:  S W Guo; D R Reed
Journal:  Ann Hum Biol       Date:  2001 Mar-Apr       Impact factor: 1.533

8.  Role of phenylthiocarbamide as a genetic marker in predicting the predisposition of disease traits in humans.

Authors:  H S Shivaprasad; P T Chaithra; P Kavitha; Suttur S Malini
Journal:  J Nat Sci Biol Med       Date:  2012-01

9.  Prevalence and Genetic Analysis of Bitter Taste Perception for Phenylthiocarbamide (PTC) Among Some Muslim Populations of Uttar Pradesh, India.

Authors:  Ruqaiya Hussain; Ahsana Shah; Mohammad Afzal
Journal:  Iran J Public Health       Date:  2014-04       Impact factor: 1.429
  9 in total

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