| Literature DB >> 1384852 |
J B Bryer1, S E Starkstein, V Votypka, R M Parikh, T R Price, R G Robinson.
Abstract
Monoamine metabolites were measured in the cerebrospinal fluid (CSF) of depressed and nondepressed patients with acute stroke lesions and in nondepressed patients without stroke lesions. Depressed stroke patients had a significantly lower concentration of CSF 5-hydroxyindoleacetic acid (5-HIAA; a serotonin metabolite) than the other two groups. These findings suggest that poststroke depression may be mediated by serotonergic mechanisms.Entities:
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Year: 1992 PMID： 1384852 DOI： 10.1176/jnp.4.4.440
Source DB: PubMed Journal: J Neuropsychiatry Clin Neurosci ISSN： 0895-0172 Impact factor: 2.198