| Literature DB >> 13841586 |
Abstract
Immature rats given minute doses of highly purified pituitary gonadotropins (follicle-stimulating hormone and luteinizing hormone) 7 to 100 days after hypophysectomy ovulated and formed corpora lutea. Neither hormone alone was effective. Luteinizing hormone repaired in part the atrophied theca interna and interstitial tissue, and follicle-stimulating hormone stimulated the development of the granulosa cells.Entities:
Keywords: GONADOTROPINS, PITUITARY/pharmacology; HYPOPHYSECTOMY/experimental; OVULATION/pharmacology
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Year: 1960 PMID： 13841586 DOI： 10.1126/science.131.3397.357
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728