Literature DB >> 13828860

The inhibition of amine oxidase and the central stimulating action of the stereoisomeric amphetamines and 1-phenylethylamines.

E GRANA, L LILLA.   

Abstract

The stereoisomers of amphetamine and 1-phenylethylamine have been studied in the rat both as central stimulants and as inhibitors of amine oxidase from brain, liver, and kidney. There was no correlation between these two effects; thus it is unlikely that the central stimulating action of amphetamine is due to inhibition of amine oxidase.

Entities:  

Keywords:  AMPHETAMINE/pharmacology; CENTRAL NERVOUS SYSTEM/pharmacology; OXIDASES/antagonists; PHENYLETHYLAMINES/pharmacology

Mesh:

Substances:

Year:  1959        PMID: 13828860      PMCID: PMC1481895          DOI: 10.1111/j.1476-5381.1959.tb00956.x

Source DB:  PubMed          Journal:  Br J Pharmacol Chemother        ISSN: 0366-0826


  3 in total

1.  The inhibition of amine oxidase and spermine oxidase by amidines.

Authors:  H BLASCHKO; J M HIMMS
Journal:  Br J Pharmacol Chemother       Date:  1955-12

2.  Benzedrine (beta-phenylisopropylamine) and brain metabolism.

Authors:  P J Mann; J H Quastel
Journal:  Biochem J       Date:  1940-03       Impact factor: 3.857

3.  Chemical structure and sympathomimetic action of amines.

Authors:  G Barger; H H Dale
Journal:  J Physiol       Date:  1910-10-11       Impact factor: 5.182

  3 in total

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