Literature DB >> 1382785

Ca2+ release from isolated sarcoplasmic reticulum of guinea-pig psoas muscle induced by K(+)-channel blockers.

Y Ishida1, H Honda, T X Watanabe.   

Abstract

A Ca(2+)-sensitive electrode was used to measure the Ca2+ concentration of the medium containing the heavy fraction of the fragmented sarcoplasmic reticulum (SR) prepared from guinea-pig psoas muscle. Among K(+)-channel blockers tested, 4-aminopyridine (4-AP), tetraethylammonium (TEA) and charybdotoxin elicited Ca2+ release from the SR, but apamin and glibenclamide did not. These results suggest that a reduction of SR K+ conductance leads to Ca2+ release from the SR.

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Year:  1992        PMID: 1382785      PMCID: PMC1907684          DOI: 10.1111/j.1476-5381.1992.tb14409.x

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN: 0007-1188            Impact factor:   8.739


  7 in total

1.  Activation by intracellular calcium of a potassium channel in cardiac sarcoplasmic reticulum.

Authors:  A Uehara; M Yasukohchi; S Ogata; I Imanaga
Journal:  Pflugers Arch       Date:  1991-02       Impact factor: 3.657

2.  Charybdotoxin, a protein inhibitor of single Ca2+-activated K+ channels from mammalian skeletal muscle.

Authors:  C Miller; E Moczydlowski; R Latorre; M Phillips
Journal:  Nature       Date:  1985 Jan 24-30       Impact factor: 49.962

3.  Kinetic studies of calcium release from sarcoplasmic reticulum in vitro.

Authors:  D H Kim; S T Ohnishi; N Ikemoto
Journal:  J Biol Chem       Date:  1983-08-25       Impact factor: 5.157

4.  Solution synthesis of charybdotoxin (ChTX), a K+ channel blocker.

Authors:  P Lambert; H Kuroda; N Chino; T X Watanabe; T Kimura; S Sakakibara
Journal:  Biochem Biophys Res Commun       Date:  1990-07-31       Impact factor: 3.575

5.  Cromakalim (BRL 34915) restores in vitro the membrane potential of depolarized human skeletal muscle fibres.

Authors:  A Spuler; F Lehmann-Horn; P Grafe
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1989-03       Impact factor: 3.000

6.  Effects of sulphonylureas and diazoxide on insulin secretion and nucleotide-sensitive channels in an insulin-secreting cell line.

Authors:  N C Sturgess; R Z Kozlowski; C A Carrington; C N Hales; M L Ashford
Journal:  Br J Pharmacol       Date:  1988-09       Impact factor: 8.739

7.  Cardiotonic action of [8]-gingerol, an activator of the Ca++-pumping adenosine triphosphatase of sarcoplasmic reticulum, in guinea pig atrial muscle.

Authors:  M Kobayashi; Y Ishida; N Shoji; Y Ohizumi
Journal:  J Pharmacol Exp Ther       Date:  1988-08       Impact factor: 4.030

  7 in total
  1 in total

1.  Nuclear KATP channels trigger nuclear Ca(2+) transients that modulate nuclear function.

Authors:  Ivan Quesada; Juan M Rovira; Franz Martin; Enrique Roche; Angel Nadal; Bernat Soria
Journal:  Proc Natl Acad Sci U S A       Date:  2002-06-27       Impact factor: 11.205

  1 in total

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