Literature DB >> 1382333

Individual differences in the cognitive and neurobiological consequences of normal aging.

P R Rapp1, D G Amaral.   

Abstract

Defining the neural basis of age-related cognitive dysfunction is a major goal of current research on aging. Compelling evidence from laboratory animals and humans indicates that aging does not inevitably lead to cognitive decline. Conducting neurobiological investigations in subjects that have previously undergone behavioral characterization has therefore emerged as a promising strategy for identifying those alterations in brain structure and function that are specifically associated with age-related cognitive impairment.

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Year:  1992        PMID： 1382333     DOI： 10.1016/0166-2236(92)90051-9

Source DB:  PubMed          Journal:  Trends Neurosci        ISSN： 0166-2236            Impact factor:   13.837


  52 in total

1.  Age-related defects in spatial memory are correlated with defects in the late phase of hippocampal long-term potentiation in vitro and are attenuated by drugs that enhance the cAMP signaling pathway.

Authors:  M E Bach; M Barad; H Son; M Zhuo; Y F Lu; R Shih; I Mansuy; R D Hawkins; E R Kandel
Journal:  Proc Natl Acad Sci U S A       Date:  1999-04-27       Impact factor: 11.205

2.  Isoflurane/nitrous oxide anesthesia induces increases in NMDA receptor subunit NR2B protein expression in the aged rat brain.

Authors:  Lana J Mawhinney; Juan Pablo de Rivero Vaccari; Ofelia F Alonso; Christopher A Jimenez; Concepción Furones; W Javier Moreno; Michael C Lewis; W Dalton Dietrich; Helen M Bramlett
Journal:  Brain Res       Date:  2011-11-07       Impact factor: 3.252

3.  Spatial learning and psychomotor performance of C57BL/6 mice: age sensitivity and reliability of individual differences.

Authors:  Nancyellen C de Fiebre; Nathalie Sumien; Michael J Forster; Christopher M de Fiebre
Journal:  Age (Dordr)       Date:  2006-12-05

Review 4.  Dissecting the age-related decline on spatial learning and memory tasks in rodent models: N-methyl-D-aspartate receptors and voltage-dependent Ca2+ channels in senescent synaptic plasticity.

Authors:  Thomas C Foster
Journal:  Prog Neurobiol       Date:  2012-01-28       Impact factor: 11.685

5.  Learning-induced survival of new neurons depends on the cognitive status of aged rats.

Authors:  Elodie Drapeau; Marie-Françoise Montaron; Sylvie Aguerre; Djoher Nora Abrous
Journal:  J Neurosci       Date:  2007-05-30       Impact factor: 6.167

Review 6.  Memory, thinking, and aging. What we know about what we know.

Authors:  L Teri; S M McCurry; R G Logsdon
Journal:  West J Med       Date:  1997-10

7.  Brain aging: impaired coding of novel environmental cues.

Authors:  H Tanila; P Sipilä; M Shapiro; H Eichenbaum
Journal:  J Neurosci       Date:  1997-07-01       Impact factor: 6.167

8.  Cardiorespiratory fitness and hippocampal volume predict faster episodic associative learning in older adults.

Authors:  Rachel C Cole; Eliot Hazeltine; Timothy B Weng; Conner Wharff; Lyndsey E DuBose; Phillip Schmid; Gardar Sigurdsson; Vincent A Magnotta; Gary L Pierce; Michelle W Voss
Journal:  Hippocampus       Date:  2019-08-28       Impact factor: 3.899

9.  The developing cholinergic system as target for environmental toxicants, nicotine and polychlorinated biphenyls (PCBs): implications for neurotoxicological processes in mice.

Authors:  P Eriksson; E Ankarberg; H Viberg; A Fredriksson
Journal:  Neurotox Res       Date:  2001-01       Impact factor: 3.911

10.  Effects of aging on paired-pulse behavior of rat somatosensory cortical neurons.

Authors:  Marianne David-Jürgens; Hubert R Dinse
Journal:  Cereb Cortex       Date:  2009-09-10       Impact factor: 5.357
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