Literature DB >> 13821346

Protection by sulfur compounds against the air pollutants ozone and nitrogen dioxide.

E J FAIRCHILD, S D MURPHY, H E STOKINGER.   

Abstract

Two distinct but related pathways of protection against the lethal effects of ozone and nitrogen dioxide are shown by (i) simultaneous inhalation of compounds that furnish -SH or -SS-, or both, and (ii) by injection of thiourea derivatives several days prior to exposure to these oxidant gases. The mechanism of (i) is believed similar to that proposed for the action of radiation-protective compounds; that of (ii) involves the development of a tolerance initiated by the thiourea against the oxidants.

Entities:  

Keywords:  NITROGEN/toxicology; OZONE/toxicology; SULFUR/pharmacology

Mesh：

Substances：

Year:  1959        PMID： 13821346     DOI： 10.1126/science.130.3379.861

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  9 in total

1.  [Ozone resistance in Escherichia coli. II. Relations with some DNA repair mechanisms (author's transl)].

Authors:  C Hamelin; Y S Chung
Journal:  Mol Gen Genet       Date:  1974-03-14

2.  Zinc nutritional status and response to lethal level of ozone exposure in rats.

Authors:  H K Kang; R A Harnish
Journal:  Bull Environ Contam Toxicol       Date:  1979-01       Impact factor: 2.151

3.  Early response of lung to low levels of ozone.

Authors:  R J Stephens; M F Sloan; M J Evans; G Freeman
Journal:  Am J Pathol       Date:  1974-01       Impact factor: 4.307

4.  Toxicity of fatty ozonides and peroxides.

Authors:  R Cortesi; O S Privett
Journal:  Lipids       Date:  1972-11       Impact factor: 1.880

5.  [Acute effects of 5 ppm NO2 on the function of the lung and circulation of healthy subjects].

Authors:  G von Nieding; H Krekeler; U Smidt; K Muysers
Journal:  Int Arch Arbeitsmed       Date:  1970

Review 6.  Experimental and clinical problems of effects of photochemical pollutants.

Authors:  B D Goldstein
Journal:  Bull N Y Acad Med       Date:  1980 Nov-Dec

7.  Ozone interaction with rodent lung. III. Oxidation of reduced glutathione and formation of mixed disulfides between protein and nonprotein sulfhydryls.

Authors:  A J DeLucia; M G Mustafa; M Z Hussain; C E Cross
Journal:  J Clin Invest       Date:  1975-04       Impact factor: 14.808

8.  Effects of thiourea tolerance on plasma histamine, and lung vascular permeability.

Authors:  S N Giri; M A Hollinger; S A Rice
Journal:  Arch Toxicol       Date:  1991       Impact factor: 5.153

9.  Lipid peroxidation and antioxidative protection mechanism in rat lungs upon acute and chronic exposure to nitrogen dioxide.

Authors:  M Sagai; T Ichinose
Journal:  Environ Health Perspect       Date:  1987-08       Impact factor: 9.031
  9 in total

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