Literature DB >> 1381955

Isochromosome 1q in acute monocytic leukemia: a new nonrandom association.

J M Hawkins1, M Wood, F Wright, L M Secker-Walker.   

Abstract

We report a case of de novo acute monocytic leukemia in a 25-year-old man in whom the sole clonal cytogenetic abnormality was an additional isochromosome 1q. Cytogenetic polymorphisms indicate that, in addition to the formation of the isochromosome, a duplication of the remaining normal chromosome 1 had taken place. Other reported cases suggest an association between acute monocytic leukemia and i(1q).

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Year:  1992        PMID: 1381955     DOI: 10.1002/gcc.2870050213

Source DB:  PubMed          Journal:  Genes Chromosomes Cancer        ISSN: 1045-2257            Impact factor:   5.006


  2 in total

1.  Characterization of a novel 350-kilodalton nuclear phosphoprotein that is specifically involved in mitotic-phase progression.

Authors:  X Zhu; M A Mancini; K H Chang; C Y Liu; C F Chen; B Shan; D Jones; T L Yang-Feng; W H Lee
Journal:  Mol Cell Biol       Date:  1995-09       Impact factor: 4.272

2.  Isochromosome 1q in childhood Burkitt lymphoma: the first reported case in Korea.

Authors:  John Hoon Rim; Hyo Sun Kim; Saeam Shin; Seo Jin Park; Jong Rak Choi
Journal:  Ann Lab Med       Date:  2015-11       Impact factor: 3.464

  2 in total

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