Literature DB >> 1381898

Intrafamilial transmission of hepatitis C virus (HCV): a major mode of spread in the Saudi Arabia population.

M N al Nasser1.   

Abstract

Age-specific prevalence of antibody to hepatitis C virus (anti-HCV) was studied in 831 Saudis (441 males, 390 females; 1-53 years old) from Al Baha region, south-west Saudi Arabia. There was a gradual exposure to HCV early in life with a gradual increase with age, reaching a peak of 5.3% in the 30-40 years age group. The overall prevalence was 3.6% and 3.1% in males and females, respectively, with no statistical difference. Comparison of positivity in family members of seven anti-HCV-positive index cases (15/44) with those of five anti-HCV-negative index cases (2/44) showed a statistically significant association (chi 2 10.5 with Yates' correction). This points to intrafamilial transmission of HCV as a route of spread among the Saudi population.

Entities:  

Keywords:  Arab Countries; Asia; Developing Countries; Diseases; Extended Family; Family And Household; Family Characteristics; Hepatitis--transmission; Measurement; Prevalence; Prospective Studies; Research Methodology; Saudi Arabia; Studies; Testing; Viral Diseases; Western Asia

Mesh:

Substances:

Year:  1992        PMID: 1381898     DOI: 10.1080/02724936.1992.11747570

Source DB:  PubMed          Journal:  Ann Trop Paediatr        ISSN: 0272-4936


  4 in total

Review 1.  Potential for human immunodeficiency virus parenteral transmission in the Middle East and North Africa: an analysis using hepatitis C virus as a proxy biomarker.

Authors:  Yousra A Mohamoud; F DeWolfe Miller; Laith J Abu-Raddad
Journal:  World J Gastroenterol       Date:  2014-09-28       Impact factor: 5.742

2.  Hepatis C virus transmission and its risk factors within families of patients infected with hepatitis C virus in southern Iran: Khuzestan.

Authors:  Eskandar Hajiani; Rahim Masjedizadeh; Jalal Hashemi; Mehrdad Azmi; Tahereh Rajabi
Journal:  World J Gastroenterol       Date:  2006-11-21       Impact factor: 5.742

3.  SASLT practice guidelines: management of hepatitis C virus infection.

Authors:  Abdullah S Alghamdi; Faisal M Sanai; Mona Ismail; Hamdan Alghamdi; Khalid Alswat; Adel Alqutub; Ibrahim Altraif; Hemant Shah; Faleh Z Alfaleh
Journal:  Saudi J Gastroenterol       Date:  2012-09       Impact factor: 2.485

4.  Virological surveillance, molecular phylogeny, and evolutionary dynamics of hepatitis C virus subtypes 1a and 4a isolates in patients from Saudi Arabia.

Authors:  Waleed H AlMalki; Imran Shahid; Ashraf N Abdalla; Ayman K Johargy; Muhammad Ahmed; Sajida Hassan
Journal:  Saudi J Biol Sci       Date:  2020-12-08       Impact factor: 4.219

  4 in total

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