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Literature DB >> 1381602

12-O-tetradecanoylphorbol 13-acetate induced differentiation in human lung squamous carcinoma cells.

G J Rabiasz¹, S P Langdon, L Anderson, A A Ritchie, W R Miller, J F Smyth.

Abstract

Three human lung squamous carcinoma cell lines (NX002, CX140 and CX143) demonstrate features of squamous differentiation including involucrin synthesis and competence to form cornified envelopes. 12-O-Tetradecanoylphorbol 13-acetate inhibits growth of these cell lines and this growth inhibition is associated with enhanced differentiation.

Entities: Chemical Disease Species

Mesh：

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Year: 1992 PMID： 1381602 PMCID： PMC1977941 DOI： 10.1038/bjc.1992.293

Source DB: PubMed Journal: Br J Cancer ISSN： 0007-0920 Impact factor: 7.640

15 in total

1. Intermediate filament and cross-linked envelope expression in human lung tumor cell lines.

Authors: S P Banks-Schlegel; A F Gazdar; C C Harris
Journal: Cancer Res Date: 1985-03 Impact factor: 12.701

2. Expression of epithelial and neural antigens in small cell and non small cell lung carcinoma.

Authors: F Moss; L G Bobrow; M N Sheppard; M Griffiths; D Rowe; P C Beverley; B Addis; R L Souhami
Journal: J Pathol Date: 1986-06 Impact factor: 7.996

3. Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures.

Authors: S M Hsu; L Raine; H Fanger
Journal: J Histochem Cytochem Date: 1981-04 Impact factor: 2.479

4. Induced cell differentiation in cancer therapy.

Authors: A Bloch
Journal: Cancer Treat Rep Date: 1984-01

5. Presence in human epidermal cells of a soluble protein precursor of the cross-linked envelope: activation of the cross-linking by calcium ions.

Authors: R H Rice; H Green
Journal: Cell Date: 1979-11 Impact factor: 41.582

12-O-tetradecanoylphorbol 13-acetate induced differentiation in human lung squamous carcinoma cells.

1. Intermediate filament and cross-linked envelope expression in human lung tumor cell lines.

2. Expression of epithelial and neural antigens in small cell and non small cell lung carcinoma.

3. Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures.

4. Induced cell differentiation in cancer therapy.

5. Presence in human epidermal cells of a soluble protein precursor of the cross-linked envelope: activation of the cross-linking by calcium ions.

6. Involucrin in lung tumors. A specific marker for squamous differentiation.

7. Epidermal growth factor receptors in lung tumours.

8. Cytokeratins in different types of human lung cancer as monitored by chain-specific monoclonal antibodies.

9. Cross-linked envelope-related markers for squamous differentiation in human lung cancer cell lines.

10. Expression of epidermal growth factor receptor (EGF-R) in human lung tumours.

1. Protein kinase C and adenylate cyclase as targets for growth inhibition of human gastric cancer cells.