Literature DB >> 13810785

The cardio-active principle in spleen.

L B COBBIN, R H THORP.   

Abstract

A substance has been demonstrated in acetone extracts of freeze-dried spleen which had cardiotonic properties on isolated papillary muscles from the cat and perfused hearts of the cat and guinea-pig. This activity of the extract could not be explained by the presence of choline, acetylcholine, histamine, 5-hydroxytryptamine, adrenaline or noradrenaline.

Entities:  

Keywords:  HEART/pharmacology; SPLEEN/chemistry

Mesh：

Substances：

Year:  1959        PMID： 13810785      PMCID： PMC1481729          DOI： 10.1111/j.1476-5381.1959.tb00264.x

Source DB:  PubMed          Journal:  Br J Pharmacol Chemother        ISSN： 0366-0826


  11 in total

1.  The isolation of a cardiac active principle from mammalian tissue.

Authors:  S HAJDU; H WEISS; E TITUS
Journal:  J Pharmacol Exp Ther       Date:  1957-05       Impact factor: 4.030

2.  Occurrence of a cardio-active principle in spleen.

Authors:  L B COBBIN; R H THORP
Journal:  Nature       Date:  1957-08-03       Impact factor: 49.962

3.  [Effects of serotonin on heart].

Authors:  A LOUBATIERES; A SASSINE; J MAUCHE
Journal:  C R Seances Soc Biol Fil       Date:  1955 Aug-Sep

4.  [Circulation reactions in the spleen-liver-mechanism after nor-adrenalin].

Authors:  W MEESMANN; J SCHMIER
Journal:  Naunyn Schmiedebergs Arch Exp Pathol Pharmakol       Date:  1955

5.  A blood outflow recorder.

Authors:  W H H ANDREWS
Journal:  J Physiol       Date:  1952-08       Impact factor: 5.182

6.  Action of liver extracts on contractility of isolated mammalian heart muscle.

Authors:  J P GREEN
Journal:  Am J Physiol       Date:  1952-08

7.  The presence of histamine and acetylcholine in the spleen of the ox and the horse.

Authors:  H H Dale; H W Dudley
Journal:  J Physiol       Date:  1929-10-23       Impact factor: 5.182

8.  The estimation of adrenaline and allied substances in blood.

Authors:  J H Gaddum; W S Peart; M Vogt
Journal:  J Physiol       Date:  1949-06-15       Impact factor: 5.182

9.  Effect of sympathetic denervation on the noradrenaline and adrenaline content of the spleen, kidney, and salivary glands in the sheep.

Authors:  U S VON EULER; A PURKHOLD
Journal:  Acta Physiol Scand       Date:  1951

10.  Bicarbonate ion and striated muscle.

Authors:  R CREESE
Journal:  J Physiol       Date:  1949-12       Impact factor: 5.182
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  3 in total

1.  [BIOLOGICAL PROPERTIES OF THE CEREBROSPINAL FLUID AND ITS CHANGES IN INCREASED BRAIN ACTIVITY].

Authors:  W ROMANOWSKI; P KRUPP; M MONNIER
Journal:  Naunyn Schmiedebergs Arch Exp Pathol Pharmakol       Date:  1964-05-29

2.  Cardio-active amines found in ox spleen extracts.

Authors:  R B Clark; S Wilkinson
Journal:  Br J Pharmacol       Date:  1971-08       Impact factor: 8.739

3.  Mechanisms regulating the cardiac output response to cyanide infusion, a model of hypoxia.

Authors:  C Liang; W E Huckabee
Journal:  J Clin Invest       Date:  1973-12       Impact factor: 14.808
  3 in total

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